English  |  正體中文  |  简体中文  |  Items with full text/Total items : 17775/20116 (88%)
Visitors : 10217958      Online Users : 480
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/31709

    標題: Constituents from the leaves of Clausena lansium and their anti-inflammatory activity
    作者: Shen, De-Yang
    Kuo, Ping-Chung
    Huang, Shiow-Chyn
    Hwang, Tsong-Long
    Chan, Yu-Yi
    Shieh, Po-Chuen
    Ngan, Nguyen Thi
    Thang, Tran Dinh
    Wu, Tian-Shung
    貢獻者: Natl Cheng Kung Univ, Coll Med, Sch Pharm,Natl Cheng Kung Univ Hosp
    Chia Nan Univ Pharm & Sci, Dept Pharm
    Chang Gung Univ, Coll Med, Grad Inst Nat Prod
    Chang Gung Univ Sci & Technol, Res Ctr Ind Human Ecol, Res Ctr Chinese Herbal Med
    Chang Gung Univ Sci & Technol, Coll Human Ecol, Grad Inst Hlth Ind Technol
    Chang Gung Mem Hosp, Dept Anesthesiol
    Southern Taiwan Univ Sci & Technol, Dept Biotechnol
    Tajen Univ, Dept Pharm
    Vinh Univ, Dept Chem
    關鍵字: Clausenalansamide
    Electronic circular dichroism
    Single-crystal X-ray diffraction analysis
    Superoxide anion generation
    日期: 2017-01
    上傳時間: 2018-11-30 15:53:45 (UTC+8)
    出版者: Springer Japan Kk
    摘要: Five new acyclic amides, clausenalansamides C-G (1-5), clausenaline G (6) and (+/-)-5-(4-methylphenyl)-gamma-valerolactone (7) reported from the natural source for the first time, were characterized from the leaves of Clausena lansium. Their structures were established by spectroscopic and spectrometric methods, and the absolute configurations of new compounds 1-5 were determined by electronic circular dichroism and single-crystal X-ray diffraction analyses. Eighteen compounds were evaluated for their anti-inflammatory activity and only imperatorin (11) and wampetin (12) displayed significant inhibition of fMLP/CB-induced superoxide anion generation with IC50 values of 1.7 +/- 0.3 and 6.8 +/- 1.1 mu M, respectively.
    關聯: Journal of Natural Medicines, v.71, n.1, pp.96-104
    Appears in Collections:[藥學系(所)] 期刊論文

    Files in This Item:

    File Description SizeFormat

    All items in CNU IR are protected by copyright, with all rights reserved.

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback