Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/24726
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 18075/20273 (89%)
造访人次 : 4464962      在线人数 : 1153
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/24726


    標題: 缺鋅對雜交吳郭魚細胞色素P4501A活性之影響
    Effect of zinc deficiency on cytochrome P4501A (CYP1A) acrivity in hybrid tilapia (Oreochromis niloticus x O. aureus)
    作者: 黃俞璇
    侯如鴻
    王明雄
    貢獻者: 保健營養系
    關鍵字: 細胞色素P4501A
    吳郭魚

    Cytochrome P4501A (CYP1A)
    tilapia
    Zinc
    日期: 2009-12-19
    上傳時間: 2011-11-09 14:32:39 (UTC+8)
    摘要: 本研究主要探討缺鋅對雜交吳郭魚肝臟的細胞色素P4501A(cytochrome P4501A,CYP1A)活性之影響。吳郭魚隨機分為缺鋅組(zinc-deficiency group)及對飼組(pair-fed control),分為餵食缺鋅飼料(5 mg Zn/ Kg 飼料) 及基礎飼料(46 mg Zn/ Kg 飼料)。經八週的飼養實驗後,缺鋅組之吳郭魚血漿中的鋅濃度則明顯低於對飼組。缺乏鋅造成吳郭魚肝臟中CYP1A相關的 aryl hydrocarbon hydroxylase (AHH) 及 ethoyresorufin-O- deethylase (EROD) 之酵素活性均有下降的趨勢。另一方面,以西方免疫分析吳郭魚CYP1A蛋白質,結果發現新的缺乏亦會造成吳郭魚CYP1A蛋白質的合成受到影響而減少。由此結果推測鋅的缺乏會影響吳郭魚CYP1A的表現。
    We investigated the effects of zinc deficiency on cytochrome P4501A (CYP1A) in hybrid tilapia. Fish were randomly assigned to one of the two dietary groups: (i) zinc-deficient (5 mg Zn/ Kg diet) ; (ii) pair-fed control (46 mg Zn/ Kg diet) for the zinc-deficient group. Each of the diets was a modified egg-white-baesd diet containing the same nutrients, but differed in the amount of zinc. After 8 weeks of the zinc-deficient diet, a decrease plasma zinc concentraion was observed in the zinc-deficient fish. Zinc-deficiency resulted in decreased aryl hydrocarbon hydroxylase (AHH), Z-ethoxyresorufin-O-deethylase (EROD), Moreover, Western immunoblot analysis using CYP1A untibody reveaked an inhibition of CYP1A protein synthesis in zinc-deficient fish at 8 weeks. The results of this stydy suggest that CYP1A are affected by zinc deficiency tilapia.
    關聯: 2009台灣水產學會學術論文發表會,起迄日:2009/12/19~2009/12/20,地點:國立高雄海洋科技大學
    显示于类别:[保健營養系(所) ] 會議論文

    文件中的档案:

    档案 大小格式浏览次数
    98_91_pro.pdf257KbAdobe PDF591检视/开启


    在CNU IR中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈