English  |  正體中文  |  简体中文  |  Items with full text/Total items : 16812/19099 (88%)
Visitors : 6370751      Online Users : 310
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/25391


    標題: Unraveling polyketide synthesis in members of the genus Aspergillus
    作者: Yi-Ming Chiang
    Berl R. Oakley
    Nancy P. Keller
    Clay C. C. Wang
    貢獻者: 藥物科技研究所
    關鍵字: Secondary metabolites
    Fungi
    Polyketide
    Nonribosomal peptides
    日期: 2010-05
    上傳時間: 2012-06-04 16:40:19 (UTC+8)
    摘要: Aspergillus species have the ability to produce a wide range of secondary metabolites including polyketides that are generated by multi-domain polyketide synthases (PKSs). Recent biochemical studies using dissected single or multiple domains from PKSs have provided deep insight into how these PKSs control the structural outcome. Moreover, the recent genome sequencing of several species has greatly facilitated the understanding of the biosynthetic pathways for these secondary metabolites. In this review, we will highlight the current knowledge regarding polyketide biosynthesis in Aspergillus based on the domain architecture of non-reducing, highly reducing, and partially reducing PKSs, and PKS-non-ribosomal peptide synthetases.
    關聯: Applied Microbiology and Biotechnology 86(6):p.1719-1736
    Appears in Collections:[藥學系(所)] 期刊論文

    Files in This Item:

    File Description SizeFormat
    99_163_j.pdf2342KbAdobe PDF250View/Open
    index.html0KbHTML513View/Open


    All items in CNU IR are protected by copyright, with all rights reserved.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback