Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/886
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    CNU IR > Pharmacy and Science > Dept. of Pharmacy > CNU Project >  Item 310902800/886
    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/886


    Title: 以電化學修飾電極對metronidazole偵測之研究
    Authors: 唐自強
    Contributors: 藥學系
    Keywords: 硝基甲嘧坐乙醇
    玻碳工作電極
    電化學修飾工作電極
    線性掃描伏安法
    metronidazole
    glassy carbon electrode
    electrochemically modified electrode
    linear-sacn voltammetry
    metronidazole
    Date: 2004
    Issue Date: 2008-06-06 16:24:44 (UTC+8)
    Publisher: 台南縣:嘉南藥理科技大學藥學系
    Abstract: 本研究針對硝基甲嘧坐乙醇
    (metronidazole)之分析,發展出使用電化
    學修飾工作電極偵測,具有高靈敏度、低
    偵測極限之電化學伏安分析法;本方法藉
    由對玻碳工作電極(Glassy Carbon
    Working Electrode, GCE)進行簡單的電化
    學處理,製成對metronidazole 偵測具有
    降低電化學還原反應電位、增大還原反應
    電流特性的活化工作電極(Activated
    Working Electrode),減少使用普通玻碳
    工作電極對metronidazole 進行電化學分
    析時,因為檢品基質效應所可能產生的干
    擾因素,以及提高偵測的靈敏度。
    本研究也針對配製樣品時常用的緩衝
    溶液種類、溶液pH 值等,對於
    metronidazole 進行電化學分析時所獲得
    偵測還原電位、還原電流值的影響進行探
    討。在使用pH 值小於8 之Britton-
    Robinson 緩衝溶液配製metronidazole 分
    析溶液時,利用活化工作電極進行線性掃描伏安法可得到較低的還原偵測電位、以及較大的還原偵測電流值。
    trochemically modified method to prepar
    a useful activated-glassy carbon working
    electrode. By using this modified method,
    one can obtain a more sensitive and
    possessing catalytic effect of reducing the
    reduction potential for the determination of
    metronidazole.
    By using this electrochemically
    modified method, more than two times of
    catalytic reduction peak current and 100mV
    lower than unmodified one, the activated
    glassy carbon electrode can give a promise
    analytical method for the analysis of
    metronidazole with linear-scan voltammetry
    method in Britton- Robinson buffer.
    Relation: CNPH9309
    Appears in Collections:[Dept. of Pharmacy] CNU Project

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