Therapeutic Effect of Human Adipocyte-derived Stem Cell-derived Exosomes on a Transgenic Mouse Model of Parkinson's Disease

doi:10.21873/invivo.13300

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標題:	Therapeutic Effect of Human Adipocyte-derived Stem Cell-derived Exosomes on a Transgenic Mouse Model of Parkinson's Disease
作者:	Chan, Lung Hsu, Wayne Chen, Kai-yun Wang, Weu Hung, Yi-chieh Hong, Chien-tai
貢獻者:	Taipei Med Univ, Shuang Ho Hosp, Dept Neurol Taipei Med Univ, Coll Med, Sch Med, Dept Neurol Taipei Med Univ, Taipei Neurosci Inst Taipei Med Univ Hosp, Dept Surg, Div Gen Surg Taipei Med Univ, Coll Med Sci & Technol, PhD Program Med Neurosci Taipei Med Univ, Coll Med, Sch Med, Dept Surg Chi Mei Med Ctr, Dept Neurosurg Chia Nan Univ Pharm & Sci, Dept Recreat & Healthcare Management Chi Mei Med Ctr, Dept Neurosurg, Dept Surg Taipei Med Univ, Shuang Ho Hosp, Dept Neurol
關鍵字:	Parkinson's disease adipocyte-derived stem cells exosome inflammation
日期:	2023
上傳時間:	2024-12-25 11:05:42 (UTC+8)
出版者:	INT INST ANTICANCER RESEARCH
摘要:	Background/Aim: Stem cell therapy and regenerative medicine are promising for treating Parkinson's disease (PD) not only for the potential for cell replacement but also for the paracrine effect of stem cell secretion, especially proteins and nucleotide-enriched exosomes. This study investigated the neuroprotective effect of exosomes secreted from human adipocyte-derived stem cells (hADSCs) on PD. Materials and Methods: hADSCs were isolated from the visceral fat tissue of individuals without PD who underwent bariatric surgery and were validated using surface markers and differentiation ability.
關聯:	In Vivo, v.37, n.5, pp.2028-2038
顯示於類別:	[行政單位] 456

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