Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/34902
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    题名: Association between vitamin D deficiency and post-acute outcomes of SARS-CoV-2 infection
    作者: Wu, Jheng-Yan
    Liu, Mei-Yuan
    Hsu, Wan-Hsuan
    Tsai, Ya-Wen
    Liu, Ting-Hui
    Huang, Po-Yu
    Chuang, Min-Hsiang
    Chin, Szu-En
    Lai, Chih-Cheng
    贡献者: Chi Mei Med Ctr, Dept Nutr
    Kaohsiung Med Univ, Grad Inst Med, Coll Med
    Natl Cheng Kung Univ, Coll Med, Dept Publ Hlth
    Chang Jung Christian Univ, Dept Nutr & Hlth Sci
    Chung Hwa Univ Med Technol, Dept Food Nutr
    Chia Nan Univ Pharm & Sci, Dept Hlth & Nutr
    Chi Mei Med Ctr, Dept Gen Med
    Chi Mei Med Ctr, Ctr Integrat Med
    Chi Mei Med Ctr, Dept Psychiat
    Chi Mei Med Ctr, Dept Internal Med
    Chang Gung Mem Hosp Chiayi, Dept Surg
    Chi Mei Med Ctr, Div Hosp Med, Dept Internal Med
    Natl Sun Yat Sen Univ, Coll Med, Sch Med
    关键词: Post-COVID-19 condition
    Long COVID
    SARS-CoV-2
    Vitamin D
    Hospitalization
    Mortality
    日期: 2024
    上传时间: 2024-12-25 11:05:21 (UTC+8)
    出版者: SPRINGER HEIDELBERG
    摘要: Objectives This study aimed to investigate the association between vitamin D deficiency (VDD) and post-acute outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.Methods This retrospective study used the TriNetX research network to identify COVID-19 patients between January 1 and November 30, 2022. Patients were matched using propensity score matching (PSM) and divided into VDD (< 20 ng/mL) and control (>= 20 ng/mL) groups. The primary outcome was a composite of post-COVID-19 condition (identified by ICD-10 code), all-cause emergency department (ED) visits, hospitalization, and death during the follow-up period (90-180 days) after the diagnosis of COVID-19.Results From an initial recruitment of 42,674 non-hospitalized patients with COVID-19 and known 25(OH)D status, a VDD group of 8300 was identified and propensity matched with 8300 controls. During the follow-up period, the VDD group had a higher risk of the primary outcome than did the control group [hazard ratio (HR) = 1.122; 95% confidence interval (CI) = 1.041-1.210]. The VDD group also had a higher risk of all-cause ED visits (HR = 1.114; 95% CI = 1.012-1.226), all-cause hospitalization (HR = 1.230; 95% CI = 1.105-1.369), and all-cause death (HR = 1.748; 95% CI = 1.047-2.290) but not post-COVID-19 condition (HR = 0.980; 95% CI = 0.630-1.523), individually.Conclusion Among the COVID-19 patients, VDD might be associated with a higher risk of all-cause ED visits, hospitalization, and death during the post-acute phase.
    關聯: European Journal of Nutrition, v.63, n.2, pp.613-622
    显示于类别:[Dept. of Health and Nutrition (including master's program)] Periodical Articles

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