Impact of Opioid-Free Anesthesia on Analgesia and Recovery Following Bariatric Surgery: a Meta-Analysis of Randomized Controlled Studies

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標題:	Impact of Opioid-Free Anesthesia on Analgesia and Recovery Following Bariatric Surgery: a Meta-Analysis of Randomized Controlled Studies
作者:	Hung, Kuo-Chuan Chiu, Chong-Chi Hsu, Chih-Wei Lin, Chien-Ming Liao, Shu-Wei Teng, I. -Chia Chen, I. -Wen Sun, Cheuk-Kwan
貢獻者:	Chi Mei Hospital Chia Nan University of Pharmacy & Science E-Da Hospital I Shou University E-Da Hospital Chang Gung University Chang Gung University Chang Gung Memorial Hospital Chi Mei Hospital E-Da Hospital
關鍵字:	obstructive sleep-apnea postoperative nausea respiratory depression remifentanil infusion general-anesthesia stress-response gastric bypass obese-patients risk-factors pain
日期:	2022
上傳時間:	2023-12-11 14:04:02 (UTC+8)
出版者:	SPRINGER
摘要:	This meta-analysis aimed at exploring the impact of opioid-free anesthesia (OFA) on pain score and opioid consumption in patients undergoing bariatric surgery (BS). Literature search identified eight eligible trials. Forest plot revealed a significantly lower pain score (mean difference (MD) = - 0.96, p = 0.0002; 318 patients), but not morphine consumption (MD = - 5.85 mg, p = 0.1; 318 patients) at postoperative 24 h in patients with OFA than in those without. Pooled analysis also showed a lower pain score (p = 0.002), morphine consumption (p = 0.0003) in the postanesthetic care unit, and risk of postoperative nausea/vomiting (p = 0.0003) in the OFA group compared to the controls. In conclusion, this meta-analysis demonstrated that opioid-free anesthesia improved pain outcomes immediately and at 24 h after surgery without a beneficial impact on opioid consumption at postoperative 24 h.
關聯:	OBESITY SURGERY, v.32, n.CB2, pp.CC2, pp.-497,
显示于类别:	[行政單位] 123

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