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https://ir.cnu.edu.tw/handle/310902800/34668
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Title: | Impact of Opioid-Free Anesthesia on Analgesia and Recovery Following Bariatric Surgery: a Meta-Analysis of Randomized Controlled Studies |
Authors: | Hung, Kuo-Chuan Chiu, Chong-Chi Hsu, Chih-Wei Lin, Chien-Ming Liao, Shu-Wei Teng, I. -Chia Chen, I. -Wen Sun, Cheuk-Kwan |
Contributors: | Chi Mei Hospital Recreation and Health Management, Chia Nan University of Pharmacy & Science E-Da Hospital I Shou University Chang Gung University Chang Gung Memorial Hospital |
Keywords: | obstructive sleep-apnea postoperative nausea respiratory depression remifentanil infusion general-anesthesia stress-response gastric bypass obese-patients risk-factors pain |
Date: | 2022 |
Issue Date: | 2023-12-11 14:04:02 (UTC+8) |
Publisher: | SPRINGER |
Abstract: | This meta-analysis aimed at exploring the impact of opioid-free anesthesia (OFA) on pain score and opioid consumption in patients undergoing bariatric surgery (BS). Literature search identified eight eligible trials. Forest plot revealed a significantly lower pain score (mean difference (MD) = - 0.96, p = 0.0002; 318 patients), but not morphine consumption (MD = - 5.85 mg, p = 0.1; 318 patients) at postoperative 24 h in patients with OFA than in those without. Pooled analysis also showed a lower pain score (p = 0.002), morphine consumption (p = 0.0003) in the postanesthetic care unit, and risk of postoperative nausea/vomiting (p = 0.0003) in the OFA group compared to the controls. In conclusion, this meta-analysis demonstrated that opioid-free anesthesia improved pain outcomes immediately and at 24 h after surgery without a beneficial impact on opioid consumption at postoperative 24 h. |
Relation: | OBESITY SURGERY, v.32, pp.3113–3124 |
Appears in Collections: | [Dept. of Recreation and Health-Care Management] Periodical Articles
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