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https://ir.cnu.edu.tw/handle/310902800/34665
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| 標題: | Suboptimal Plasma Vitamin C Is Associated with Lower Bone Mineral Density in Young and Early Middle-Aged Men: A Retrospective Cross-Sectional Study |
| 作者: | Lan, Kuo-Mao
Wang, Li-Kai
Lin, Yao-Tsung
Hung, Kuo-Chuan
Wu, Li-Ching
Ho, Chung-Han
Chang, Chia-Yu
Chen, Jen-Yin |
| 貢獻者: | Chi Mei Hospital
Chi Mei Hospital
Chia Nan University of Pharmacy & Science
Chi Mei Hospital
National Sun Yat Sen University
Chi Mei Hospital
Chi Mei Hospital
Southern Taiwan University of Science & Technology |
| 關鍵字: | body-mass index
25-hydroxyvitamin d
postmenopausal women
serum concentrations
adult patients
ascorbic-acid
d deficiency
risk-factors
osteoporosis
fractures |
| 日期: | 2022 |
| 上傳時間: | 2023-12-11 14:03:52 (UTC+8) |
| 出版者: | MDPI |
| 摘要: | Background: This study was conducted to evaluate associations between bone mineral density (BMD) and four selected circulating nutrients, particularly vitamin C, among adults aged 20-49 years. Methods: In this retrospective cross-sectional study, the lumbar spine BMD of 866 men and 589 women were measured by dual-energy X-ray absorptiometry and divided into tertiles, respectively. Logistic regressions were used to identify the predictors of low BMD by comparing subjects with the highest BMD to those with the lowest. Results: Multivariate logistic regressions identified suboptimal plasma vitamin C (adjusted odds ratio (AOR) 1.64, 95% confidence interval (CI) 1.16, 2.31), suboptimal serum vitamin B12 (AOR 2.05, 95% CI 1.02, 4.12), and low BMI (BMI < 23) (AOR 1.68, 95% CI 1.12, 2.53) as independent predictors for low BMD in men. In women, low BMI was the only independent predictor for low BMD. Plasma vitamin C, categorized as suboptimal (<= 8.8 mg/L) and sufficient (>8.8 mg/L), was positively significantly correlated with the lumbar spine BMD in men, but there was no association in women. Conclusions: Plasma vitamin C, categorized as suboptimal and sufficient, was positively associated with the lumbar spine BMD in young and early middle-aged men. A well-designed cohort study is needed to confirm the findings. |
| 關聯: | NUTRIENTS, v.14, n.CB2, pp.CC2, pp.-3124, |
| 顯示於類別: | [行政單位] 123
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