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    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/34481


    標題: Potentially Inappropriate Medication among Older Patients Who Are Frequent Users of Outpatient Services
    作者: Hsu, Kung-Chuan
    Lu, Hai-Lin
    Kuan, Chi-Ming
    Wu, Jin-Song
    Huang, Chyn-Liang
    Lin, Pu-Hua
    Trezise, Damien
    Wang, Tzu-Chueh
    貢獻者: Giraffe Pharm
    Chia Nan Univ Pharm & Sci, Dept Informat Management
    Minist Hlth & Welf, Kaoping Div, Natl Hlth Insurance Adm
    Minist Hlth & Welf, Taiwan Food & Drug Adm, Div Med Prod
    Chia Nan Univ Pharm & Sci, Dept Appl Foreign Languages
    Chia Nan Univ Pharm & Sci, Dept Pharm
    關鍵字: older adults care
    polypharmacy
    potentially inappropriate medication
    日期: 2021
    上傳時間: 2023-11-11 11:56:38 (UTC+8)
    出版者: MDPI
    摘要: Aging is accompanied by changes in organ degeneration, and susceptibility to multiple diseases, leading to the frequent occurrence of adverse drug reactions resulting from polypharmacy (PP) and potentially inappropriate medications (PIM) in older patients. This study employs a retrospective cohort design and investigates the association of PP with PIM among older patients with high rates of medical utilization. Using records from a national pharmaceutical care database, an experimental group is formed from patients meeting these criteria, who are then offered home pharmaceutical care. Correspondingly, a control group is formed by identifying older patients with regular levels of use of medical services who had been dispensed medications at community pharmacies. Multivariate logistic regression is performed to assess the association between the rate of PIM and variables, including age, gender, and PP. The study finds that experimental PP participants had a higher rate of PIM prescription (odds ratio (OR) = 5.4) than non-PP control participants (all p < 0.001). In clinical practice, additional caution is required to avoid PIMs. Patients engaged in continuously using long-term medication should take precautions in daily life to alleviate related discomforts. Pharmacists should serve as a bridge between patients and physicians to enhance their health and improve their quality of life.
    關聯: INT J ENV RES PUB HE, v.18, n.3, pp.985
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