Potentially Inappropriate Medication among Older Patients Who Are Frequent Users of Outpatient Services

doi:10.3390/ijerph18030985

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Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/34481

Title:	Potentially Inappropriate Medication among Older Patients Who Are Frequent Users of Outpatient Services
Authors:	Hsu, Kung-Chuan Lu, Hai-Lin Kuan, Chi-Ming Wu, Jin-Song Huang, Chyn-Liang Lin, Pu-Hua Trezise, Damien Wang, Tzu-Chueh
Contributors:	Giraffe Pharm Chia Nan Univ Pharm & Sci, Dept Informat Management Minist Hlth & Welf, Kaoping Div, Natl Hlth Insurance Adm Minist Hlth & Welf, Taiwan Food & Drug Adm, Div Med Prod Chia Nan Univ Pharm & Sci, Dept Appl Foreign Languages Chia Nan Univ Pharm & Sci, Dept Pharm
Keywords:	older adults care polypharmacy potentially inappropriate medication
Date:	2021
Issue Date:	2023-11-11 11:56:38 (UTC+8)
Publisher:	MDPI
Abstract:	Aging is accompanied by changes in organ degeneration, and susceptibility to multiple diseases, leading to the frequent occurrence of adverse drug reactions resulting from polypharmacy (PP) and potentially inappropriate medications (PIM) in older patients. This study employs a retrospective cohort design and investigates the association of PP with PIM among older patients with high rates of medical utilization. Using records from a national pharmaceutical care database, an experimental group is formed from patients meeting these criteria, who are then offered home pharmaceutical care. Correspondingly, a control group is formed by identifying older patients with regular levels of use of medical services who had been dispensed medications at community pharmacies. Multivariate logistic regression is performed to assess the association between the rate of PIM and variables, including age, gender, and PP. The study finds that experimental PP participants had a higher rate of PIM prescription (odds ratio (OR) = 5.4) than non-PP control participants (all p < 0.001). In clinical practice, additional caution is required to avoid PIMs. Patients engaged in continuously using long-term medication should take precautions in daily life to alleviate related discomforts. Pharmacists should serve as a bridge between patients and physicians to enhance their health and improve their quality of life.
Relation:	INT J ENV RES PUB HE, v.18, n.3, pp.985
Appears in Collections:	[Dept. of Information Management] Periodical Articles [Dept. of Applied Foreign Languages] Periodical Articles [Dept. of Pharmacy] Periodical Articles

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