Sole adjuvant intraoperative breast radiotherapy in Taiwan: a single-center experience

doi:10.1186/s13058-021-01421-y

CNU IR > Pharmacy and Science > Dept. of Cosmetic Science and institute of cosmetic science > Periodical Articles > Item 310902800/34449

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/34449

题名:	Sole adjuvant intraoperative breast radiotherapy in Taiwan: a single-center experience
作者:	Yang, Hsin-Yi Tu, Chi-Wen Chen, Chien-Chin Lee, Cheng-Yen Hsu, Yu-Chen
贡献者:	Ditmans Med Fdn, Clin Med Res Ctr, Chia Yi Christian Hosp Ditmans Med Fdn, Clin Med Res Ctr, Chia Yi Christian Hosp, Dept Surg Ditmanson Med Fdn, Chia Yi Christian Hosp, Dept Pathol Chia Nan Univ Pharm & Sci, Dept Cosmet Sci Ditmanson Med Fdn, Chia Yi Christian Hosp, Dept Radiat Therapy & Oncol
关键词:	Breast cancer Intraoperative radiotherapy Whole breast external beam radiotherapy
日期:	2021
上传时间:	2023-11-11 11:53:24 (UTC+8)
出版者:	BMC
摘要:	Introduction Intraoperative radiotherapy (IORT) is more convenient than standard whole breast external beam radiotherapy (EBRT) as a sole adjuvant radiotherapy for breast cancer. The impact of age on breast cancer course and treatment strategy is still under investigation, and the peak age for breast cancer in Taiwan is much younger than that in Western countries. We aimed to review the oncological outcomes of sole IORT compared with standard EBRT in a country with younger breast cancer patients. Patients and methods We reviewed patients with invasive breast cancer who received breast-conserving surgery (BCS) from September 2014 to December 2016. The clinicopathologic characteristics and oncological outcomes of eligible patients who received EBRT or IORT as sole adjuvant radiotherapy after BCS were collected and reviewed. Results A total of 170 patients were enrolled with a mean follow-up time of 3.53 +/- 0.82 years. The risk of locoregional recurrence was 2.44% for EBRT versus 10.64% for IORT (p = 0.024). IORT was a significant risk factor of locoregional recurrence (p = 0.005). The hazard ratios (HRs) for locoregional recurrence in the IORT group compared with the EBRT group were significantly higher in non-suitable risk group patients (HR = 7.02, p = 0.009) and in patients under 50 years old (HR = 10.42, p = 0.011). Conclusions Locoregional recurrence was significantly higher in patients who received IORT than in those who underwent EBRT. IORT should not be used alone in patients under 50 years old who do not belong to a suitable group.
關聯:	BREAST CANCER RES, v.23, n.1, pp.43
显示于类别:	[Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles

文件中的档案:

档案	描述	大小	格式	浏览次数
index.html		0Kb	HTML	474	检视/开启
s13058-021-01421-y.pdf		579Kb	Adobe PDF	167	检视/开启

在CNU IR中所有的数据项都受到原著作权保护.

TAIR相关文章

数据加载中.....