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| 標題: | Adherence to Nutritional Supplementation Determines Postoperative Vitamin D Status, but Not Levels of Bone Resorption Marker, in Sleeve-Gastrectomy Patients |
| 作者: | Liao, Wen-Ling
Yang, Wan-Ching
Shaw, Huey-Mei
Lin, Chi-Hsuan
Wu, Chin-Ching
Hsu, Wan-Lin
Lu, Yao-Cheng
Chao, Pei-Min
Huang, Chih-Kun |
| 貢獻者: | China Med Univ, Grad Inst Integrated Med
China Med Univ Hosp, Ctr Personalized Med
China Med Univ, Dept Nutr
Chia Nan Univ Pharm & Sci, Dept Hlth & Nutr
China Med Univ Hosp, Body Sci & Metab Disorders Int BMI Med Ctr
China Med Univ, Dept Publ Hlth |
| 關鍵字: | Adherence
Supplement
Nutritional status
C-terminal telopeptide of type I collage
Sleeve gastrectomy |
| 日期: | 2021 |
| 上傳時間: | 2023-11-11 11:51:19 (UTC+8) |
| 出版者: | SPRINGER |
| 摘要: | Background Taking advantage of isomeric form of vitamin E in the supplement, adherence to supplement could be evaluated by changes in circulating alpha- and gamma-tocopherol concentrations. Accordingly, effects of supplementation on postoperative nutrition and bone metabolism were studied in terms of adherence. Methods Thirty-eight SG patients were all prescribed a postoperative nutritional supplement containing a low dose of vitamin D (600 IU) and calcium (200 mg). Blood samples were collected prior to (M0) and 6 months after (M6) surgery and concentrations of nutrients and C-terminal telopeptide of type I collage (CTX), a marker of bone resorption, were measured. Adherence and non-adherence were stratified according to change (o, M6-M0) in serum alpha-tocopherol concentrations (> 0 vs. <= 0, respectively). Results When M0 and M6 were compared, there were significant increases in serum concentrations of 25(OH)D, alpha-tocopherol and selenium, whereas there were reductions in parathyroid hormone, ferritin, and gamma-tocopherol. At M6, the prevalence of vitamin D insufficiency (25(OH)D < 30 ng/mL) and high CTX were 72 and 26%, respectively. When comparison was made between adherence and non-adherence, only o25(OH)D concentrations, but no other nutrients nor postoperative CTX differed. Multiple linear regression demonstrated that postoperative vitamin D status was independently associated with its preoperative concentrations (beta = 0.85, p < 0.001) and adherence (beta = 0.52, p < 0.05). Conclusion SG patients' adherence to supplementation, even with a low dose of vitamin D and calcium, determined vitamin D status but not bone resorption marker concentrations, at least within 6 months after surgery. |
| 關聯: | OBES SURG, v.31, n.8, pp.3707-3714 |
| 顯示於類別: | [保健營養系(所) ] 期刊論文
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