Adherence to Nutritional Supplementation Determines Postoperative Vitamin D Status, but Not Levels of Bone Resorption Marker, in Sleeve-Gastrectomy Patients

doi:10.1007/s11695-021-05484-w

CNU IR > Pharmacy and Science > Dept. of Health and Nutrition (including master's program) > Periodical Articles > Item 310902800/34418

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/34418

Title:	Adherence to Nutritional Supplementation Determines Postoperative Vitamin D Status, but Not Levels of Bone Resorption Marker, in Sleeve-Gastrectomy Patients
Authors:	Liao, Wen-Ling Yang, Wan-Ching Shaw, Huey-Mei Lin, Chi-Hsuan Wu, Chin-Ching Hsu, Wan-Lin Lu, Yao-Cheng Chao, Pei-Min Huang, Chih-Kun
Contributors:	China Med Univ, Grad Inst Integrated Med China Med Univ Hosp, Ctr Personalized Med China Med Univ, Dept Nutr Chia Nan Univ Pharm & Sci, Dept Hlth & Nutr China Med Univ Hosp, Body Sci & Metab Disorders Int BMI Med Ctr China Med Univ, Dept Publ Hlth
Keywords:	Adherence Supplement Nutritional status C-terminal telopeptide of type I collage Sleeve gastrectomy
Date:	2021
Issue Date:	2023-11-11 11:51:19 (UTC+8)
Publisher:	SPRINGER
Abstract:	Background Taking advantage of isomeric form of vitamin E in the supplement, adherence to supplement could be evaluated by changes in circulating alpha- and gamma-tocopherol concentrations. Accordingly, effects of supplementation on postoperative nutrition and bone metabolism were studied in terms of adherence. Methods Thirty-eight SG patients were all prescribed a postoperative nutritional supplement containing a low dose of vitamin D (600 IU) and calcium (200 mg). Blood samples were collected prior to (M0) and 6 months after (M6) surgery and concentrations of nutrients and C-terminal telopeptide of type I collage (CTX), a marker of bone resorption, were measured. Adherence and non-adherence were stratified according to change (o, M6-M0) in serum alpha-tocopherol concentrations (> 0 vs. <= 0, respectively). Results When M0 and M6 were compared, there were significant increases in serum concentrations of 25(OH)D, alpha-tocopherol and selenium, whereas there were reductions in parathyroid hormone, ferritin, and gamma-tocopherol. At M6, the prevalence of vitamin D insufficiency (25(OH)D < 30 ng/mL) and high CTX were 72 and 26%, respectively. When comparison was made between adherence and non-adherence, only o25(OH)D concentrations, but no other nutrients nor postoperative CTX differed. Multiple linear regression demonstrated that postoperative vitamin D status was independently associated with its preoperative concentrations (beta = 0.85, p < 0.001) and adherence (beta = 0.52, p < 0.05). Conclusion SG patients' adherence to supplementation, even with a low dose of vitamin D and calcium, determined vitamin D status but not bone resorption marker concentrations, at least within 6 months after surgery.
Relation:	OBES SURG, v.31, n.8, pp.3707-3714
Appears in Collections:	[Dept. of Health and Nutrition (including master's program)] Periodical Articles

Files in This Item:

File	Description	Size	Format
index.html		0Kb	HTML	205	View/Open

Loading...