Collagen formula with Chinese herbal medicine can improve skin condition and reduce inflammation: a double-blind, randomized, placebo-controlled trial

doi:10.1108/NFS-02-2021-0065

CNU IR > Pharmacy and Science > Dept. of Cosmetic Science and institute of cosmetic science > Periodical Articles > Item 310902800/34407

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/34407

Title:	Collagen formula with Chinese herbal medicine can improve skin condition and reduce inflammation: a double-blind, randomized, placebo-controlled trial
Authors:	Chang, Hui-Chun Lin, Yung-Kai Liang, Chia-Hua Huang, Hsin-Wei Lin, Yung-Hao Lin, Yung-Hsiang Hu, Wei-Chun Chiang, Chi Fu
Contributors:	TCI Co Ltd, Res & Design Ctr Natl Taiwan Ocean Univ, Inst Food Safety & Risk Management Chia Nan Univ Pharm & Sci, Dept Cosmet Sci Chia Nan Univ Pharm & Sci, Inst Cosmet Sci TCI Gene Inc, Res & Design Ctr TCI Co Ltd, Global Business Ctr
Keywords:	Chinese herbal extracts Hydrolyzed collagen Skin aging
Date:	2021
Issue Date:	2023-11-11 11:50:14 (UTC+8)
Publisher:	EMERALD GROUP PUBLISHING LTD
Abstract:	Purpose Population aging was a global trend, and the most obvious thing after aging was the change in skin appearance. Therefore, the active ingredients that delay skin aging were particularly noticed. Past studies had pointed out that Chinese herbal extracts can improve skin elasticity, reduce wrinkles and melanin precipitation. The purpose of this paper is to explore whether combining hydrolyzed collagen with Chinese herbal extracts can improve skin conditions and achieve anti-inflammatory effects. Design/methodology/approach Fifty subjects were randomly divided into collagen or placebo groups, and one bottle of collagen or placebo drink was used every day for four weeks, after which skin and inflammatory factors were tested. Findings In comparison with the baseline results, the skin parameters were improving after four-week intervention. In addition, the IL-6, IL-8, TNF-a were significantly decreased and tissue inhibitor matrix metalloproteinase 1 (TIMP-1) was increased after four-week hydrolyzed collagen intervention. Originality/value This study showed that hydrolyzed collagen combined with Chinese herbal extracts can improve the condition of the skin, and can also reduce inflammatory associated factors, thereby achieving anti-aging effects.
Relation:	NUTR FOOD SCI, v.51, n.8, pp.1236-1244
Appears in Collections:	[Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles

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