Sugammadex induced bradycardia and hypotension A case report and literature review

doi:10.1097/MD.0000000000026796

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標題:	Sugammadex induced bradycardia and hypotension A case report and literature review
作者:	Teng, I-Chia Chang, Ying-Jen Lin, Yao-Tsung Chu, Chin-Chen Chen, Jen-Yin Wu, Zhi-Fu
貢獻者:	Chi Mei Med Ctr, Dept Anesthesiol Chia Nan Univ Pharm & Sci, Dept Food Sci & Technol Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Dept Anesthesiol Tri Serv Gen Hosp Natl Def Med Ctr, Dept Anesthesiol
關鍵字:	bradycardia cardiac arrest hypotension sugammadex
日期:	2021
上傳時間:	2023-11-11 11:48:52 (UTC+8)
出版者:	LIPPINCOTT WILLIAMS & WILKINS
摘要:	Rationale: There is evidence that sugammadex can facilitate extubation post-surgery and attenuate postoperative pulmonary complications resulting from postoperative residual neuromuscular blockade. However, it may induce adverse effects, including bronchospasm, laryngospasm, bradycardia, hypotension, and cardiac arrest. Here, we present a case of sugammadex-induced bradycardia and hypotension. Patient concerns: An 82-year-old female received video-assisted thoracic surgery decortication and wedge resection of the lung for empyema. Post-surgery, she developed bradycardia, hypotension, hypoxia, and weakness. Diagnoses: The patient was suspected to have sugammadex-induced bradycardia, hypotension, hypoxia and weakness. Interventions: The patient received immediate treatment with atropine (0.5 mg) for bradycardia. Glycopyrrolate (0.1 mg) and neostigmine (1 mg) were administered to improve the train-of-four (TOF) ratio. Outcomes: Following initial management, we observed improvement in the hemodynamics of the patient. She was discharged without any sequelae. Lessons: Sugammadex-induced bradycardia or cardiac arrest are rare; however, anesthesiologists must consider the possibility of the occurrence of such events and initiate appropriate management measures. Immediate treatment with atropine and inotropic or vasopressors is warranted if the patient presents with bradycardia.
關聯:	MEDICINE, v.100, n.30
显示于类别:	[ 食品科技系 ] 期刊論文

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