Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/34388
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    標題: Sugammadex induced bradycardia and hypotension A case report and literature review
    作者: Teng, I-Chia
    Chang, Ying-Jen
    Lin, Yao-Tsung
    Chu, Chin-Chen
    Chen, Jen-Yin
    Wu, Zhi-Fu
    貢獻者: Chi Mei Med Ctr, Dept Anesthesiol
    Chia Nan Univ Pharm & Sci, Dept Food Sci & Technol
    Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Dept Anesthesiol
    Tri Serv Gen Hosp
    Natl Def Med Ctr, Dept Anesthesiol
    關鍵字: bradycardia
    cardiac arrest
    hypotension
    sugammadex
    日期: 2021
    上傳時間: 2023-11-11 11:48:52 (UTC+8)
    出版者: LIPPINCOTT WILLIAMS & WILKINS
    摘要: Rationale: There is evidence that sugammadex can facilitate extubation post-surgery and attenuate postoperative pulmonary complications resulting from postoperative residual neuromuscular blockade. However, it may induce adverse effects, including bronchospasm, laryngospasm, bradycardia, hypotension, and cardiac arrest. Here, we present a case of sugammadex-induced bradycardia and hypotension. Patient concerns: An 82-year-old female received video-assisted thoracic surgery decortication and wedge resection of the lung for empyema. Post-surgery, she developed bradycardia, hypotension, hypoxia, and weakness. Diagnoses: The patient was suspected to have sugammadex-induced bradycardia, hypotension, hypoxia and weakness. Interventions: The patient received immediate treatment with atropine (0.5 mg) for bradycardia. Glycopyrrolate (0.1 mg) and neostigmine (1 mg) were administered to improve the train-of-four (TOF) ratio. Outcomes: Following initial management, we observed improvement in the hemodynamics of the patient. She was discharged without any sequelae. Lessons: Sugammadex-induced bradycardia or cardiac arrest are rare; however, anesthesiologists must consider the possibility of the occurrence of such events and initiate appropriate management measures. Immediate treatment with atropine and inotropic or vasopressors is warranted if the patient presents with bradycardia.
    關聯: MEDICINE, v.100, n.30
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