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    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/34381

    標題: Efficacy and airway complications of Parker Flex-Tip tubes and standard endotracheal tubes during airway manipulation A meta-analysis and trial sequential analysis
    作者: Hung, Kuo-Chuan
    Chen, Jen-Yin
    Feng, I-Jung
    Chiang, Min-Hsien
    Wu, Shao-Chun
    Chen, I-Wen
    Lin, Yao-Tsung
    Chang, Ying-Jen
    Wu, Zhi-Fu
    Lu, Hsiao-Feng
    Sun, Cheuk-Kwan
    貢獻者: Chi Mei Med Ctr, Dept Anaesthesiol
    Chia Nan Univ Pharm & Sci, Dept Hlth & Nutr
    Chia Nan Univ Pharm & Sci, Dept Senior Citizen Serv Management
    Natl Sun Yat Sen Univ, Inst Precis Med
    Chang Gung Univ, Dept Anaesthesiol, Kaohsiung Chang Gung Mem Hosp, Coll Med
    Chia Nan Univ Pharm & Sci, Ctr Gen Educ
    E Da Hosp, Dept Emergency Med
    I Shou Univ, Coll Med
    日期: 2021
    上傳時間: 2023-11-11 11:48:28 (UTC+8)
    摘要: BACKGROUND Despite reported superior intubation outcomes associated with Parker Flex-Tip (PFT) tubes compared with those associated with standard polyvinylchloride tubes, the efficacy and safety of PFT tubes remain uncertain. OBJECTIVES To compare the intubation outcomes between PFT and conventional standard polyvinylchloride tubes. DESIGN Meta-analysis of randomised controlled trials. DATA SOURCES Embase, Medline, Google Scholar, PubMed and the Cochrane controlled trials register from inception until 3 January 2021. ELIGIBILITY CRITERIA All randomised trials comparing intubation outcomes between PFT (PFT group) and standard polyvinylchloride (standard polyvinylchloride group) tubes. RESULTS Analysis of the 13 eligible trials showed no significant difference in successful first-attempt intubation rate [risk ratio (RR) 1.20, 95% confidence interval (CI) 0.99 to 1.44] (6 trials, 568 participants), trauma risk (RR 0.83, 95% CI 0.67 to 1.03) (5 trials, 501 participants) as well as the overall risks of epistaxis (RR 0.58, 95% CI 0.26 to 1.31) (3 trials, 262 participants), sore throat (RR 0.90, 95% CI 0.70 to 1.17) (4 trials, 451 participants) and hoarseness (RR 0.71, 95% CI 0.44 to 1.14) (4 trials, 451 participants) between the two groups. However, the intubation time was slightly shorter (weighted mean difference -4.2 s, 95% CI -7.4 to -1.0 s) (8 trials, 759 participants) and the risks of severe epistaxis (RR 0.15, 95% CI 0.03 to 0.84) (3 trials, 262 participants) and overall difficulty in airway manipulation (RR 0.48, 95% CI 0.29 to 0.80) (8 trials, 647 participants) were lower in the PFT group than those in the standard polyvinylchloride group. Trial sequential analysis conclusively confirmed a shorter intubation time with PFT tubes than with standard polyvinylchloride tubes, whereas other intubation outcomes were inconclusive. CONCLUSION The use of PFT tubes for airway manipulation was associated with a shorter intubation time compared with the standard polyvinylchloride tubes. The results of trial sequential analysis suggest the need for further trials and meta-analysis to compare other intubation outcomes associated with the two devices.
    關聯: EUR J ANAESTH, v.38, n.8, pp.813-824
    Appears in Collections:[保健營養系(所) ] 期刊論文
    [高齡福祉養生管理系] 期刊論文
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