Efficacy and airway complications of Parker Flex-Tip tubes and standard endotracheal tubes during airway manipulation A meta-analysis and trial sequential analysis

doi:10.1097/EJA.0000000000001539

CNU IR > Pharmacy and Science > Dept. of Health and Nutrition (including master's program) > Periodical Articles > Item 310902800/34381

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/34381

Title:	Efficacy and airway complications of Parker Flex-Tip tubes and standard endotracheal tubes during airway manipulation A meta-analysis and trial sequential analysis
Authors:	Hung, Kuo-Chuan Chen, Jen-Yin Feng, I-Jung Chiang, Min-Hsien Wu, Shao-Chun Chen, I-Wen Lin, Yao-Tsung Chang, Ying-Jen Wu, Zhi-Fu Lu, Hsiao-Feng Sun, Cheuk-Kwan
Contributors:	Chi Mei Med Ctr, Dept Anaesthesiol Chia Nan Univ Pharm & Sci, Dept Hlth & Nutr Chia Nan Univ Pharm & Sci, Dept Senior Citizen Serv Management Natl Sun Yat Sen Univ, Inst Precis Med Chang Gung Univ, Dept Anaesthesiol, Kaohsiung Chang Gung Mem Hosp, Coll Med Chia Nan Univ Pharm & Sci, Ctr Gen Educ E Da Hosp, Dept Emergency Med I Shou Univ, Coll Med
Keywords:	FIBEROPTIC OROTRACHEAL INTUBATION POSTERIOR-FACING BEVEL TRACHEAL TUBE NASOTRACHEAL INTUBATION DIRECT LARYNGOSCOPY SORE THROAT EPISTAXIS VIDEOLARYNGOSCOPY BRONCHOSCOPE IMPINGEMENT
Date:	2021
Issue Date:	2023-11-11 11:48:28 (UTC+8)
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Abstract:	BACKGROUND Despite reported superior intubation outcomes associated with Parker Flex-Tip (PFT) tubes compared with those associated with standard polyvinylchloride tubes, the efficacy and safety of PFT tubes remain uncertain. OBJECTIVES To compare the intubation outcomes between PFT and conventional standard polyvinylchloride tubes. DESIGN Meta-analysis of randomised controlled trials. DATA SOURCES Embase, Medline, Google Scholar, PubMed and the Cochrane controlled trials register from inception until 3 January 2021. ELIGIBILITY CRITERIA All randomised trials comparing intubation outcomes between PFT (PFT group) and standard polyvinylchloride (standard polyvinylchloride group) tubes. RESULTS Analysis of the 13 eligible trials showed no significant difference in successful first-attempt intubation rate [risk ratio (RR) 1.20, 95% confidence interval (CI) 0.99 to 1.44] (6 trials, 568 participants), trauma risk (RR 0.83, 95% CI 0.67 to 1.03) (5 trials, 501 participants) as well as the overall risks of epistaxis (RR 0.58, 95% CI 0.26 to 1.31) (3 trials, 262 participants), sore throat (RR 0.90, 95% CI 0.70 to 1.17) (4 trials, 451 participants) and hoarseness (RR 0.71, 95% CI 0.44 to 1.14) (4 trials, 451 participants) between the two groups. However, the intubation time was slightly shorter (weighted mean difference -4.2 s, 95% CI -7.4 to -1.0 s) (8 trials, 759 participants) and the risks of severe epistaxis (RR 0.15, 95% CI 0.03 to 0.84) (3 trials, 262 participants) and overall difficulty in airway manipulation (RR 0.48, 95% CI 0.29 to 0.80) (8 trials, 647 participants) were lower in the PFT group than those in the standard polyvinylchloride group. Trial sequential analysis conclusively confirmed a shorter intubation time with PFT tubes than with standard polyvinylchloride tubes, whereas other intubation outcomes were inconclusive. CONCLUSION The use of PFT tubes for airway manipulation was associated with a shorter intubation time compared with the standard polyvinylchloride tubes. The results of trial sequential analysis suggest the need for further trials and meta-analysis to compare other intubation outcomes associated with the two devices.
Relation:	EUR J ANAESTH, v.38, n.8, pp.813-824
Appears in Collections:	[Dept. of Health and Nutrition (including master's program)] Periodical Articles [Dept. of Senior Service and Health Management] Periodical Articles [The Center For General Education] Periodical Articles

Files in This Item:

File	Description	Size	Format
EJA.0000000000001539.pdf		563Kb	Adobe PDF	98	View/Open
index.html		0Kb	HTML	215	View/Open

Loading...