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| 標題: | Coffee pulp supplement affects antioxidant status and favors anti-aging of skin in healthy subjects |
| 作者: | Tseng, Ya-Ping
Liu, Cheng
Chan, Leong-Perng
Liang, Chia-Hua |
| 貢獻者: | Natl Cheng Kung Univ, Inst Basic Med Sci
Shu Zen Jr Coll Med & Management, Dept Hlth & Beauty
Shu Zen Jr Coll Med & Management, Dept Optometry
Shu Zen Jr Coll Med & Management, Dept Dent Technol
Kaohsiung Med Univ, Kaohsiung Municipal Ta Tung Hosp, Dept Otorhinolaryngol Head & Neck Surg
Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Coll Med, Dept Otorhinolaryngol Head & Neck Surg,Fac Med
Chia Nan Univ Pharm & Sci, Dept Cosmet Sci
Chia Nan Univ Pharm & Sci, Inst Cosmet Sci |
| 關鍵字: | anti-aging
antioxidant
coffee
skin |
| 日期: | 2021 |
| 上傳時間: | 2023-11-11 11:48:19 (UTC+8) |
| 出版者: | WILEY |
| 摘要: | Background Coffee and coffee products are known potentially to reduce levels of oxidative stress biomarkers in humans. Objective This investigation evaluates the effects of coffee pulp extract as a functional supplement (in coffee pulp drink, CPD) and a cosmetic ingredient (coffee pulp serum, CPS). Patients/Methods The effects of CPD and CPS for anti-oxidation and anti-aging were investigated. Forty subjects were randomly allocated to CPD or placebo drink groups (50 ml of a CPD/placebo drink daily for 8 weeks for each subject), and another 40 subjects were recruited to CPS or placebo serum groups (about 3 ml of a CPS/placebo serum day and night/daily for 4 weeks for each subject) in a double-blind study. Results The CPD and CPS (20%) can increase free radical scavenging activities by 93.3% and 85% (p < 0.001) for DPPH, 94.5% and 61.3% (p < 0.01) for ABTS center dot(+), 43.8% and 15.3% (p < 0.05) for NO center dot than placebo. The inhibition of tyrosinase activity was increased by 91.6% and 51.0% (p < 0.05) after CPD and CPS application. The CPD comprehensively improved the moisture, brightness, elasticity, spotting, texture, and collagen content of skin for most subjects after 8 weeks, relative to the baseline without treatment (p < 0.05). After 4 weeks of CPS serum consumption, the brightness, elasticity, spotting, UV spots, and collagen content of skin were slightly better than those at week 0 (p < 0.05). Conclusions The daily consumption of coffee pulp extract products can slow the skin aging process and improve skin health. |
| 關聯: | J COSMET DERMATOL-US, v.21, n.5, pp.2189-2199 |
| 顯示於類別: | [化妝品應用與管理系(所)] 期刊論文
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