Coffee pulp supplement affects antioxidant status and favors anti-aging of skin in healthy subjects

doi:10.1111/jocd.14341

Chia Nan University of Pharmacy & Science Institutional Repository > 藥理學院 > 化妝品應用與管理系(所) > 期刊論文 > Item 310902800/34378

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標題:	Coffee pulp supplement affects antioxidant status and favors anti-aging of skin in healthy subjects
作者:	Tseng, Ya-Ping Liu, Cheng Chan, Leong-Perng Liang, Chia-Hua
貢獻者:	Natl Cheng Kung Univ, Inst Basic Med Sci Shu Zen Jr Coll Med & Management, Dept Hlth & Beauty Shu Zen Jr Coll Med & Management, Dept Optometry Shu Zen Jr Coll Med & Management, Dept Dent Technol Kaohsiung Med Univ, Kaohsiung Municipal Ta Tung Hosp, Dept Otorhinolaryngol Head & Neck Surg Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Coll Med, Dept Otorhinolaryngol Head & Neck Surg,Fac Med Chia Nan Univ Pharm & Sci, Dept Cosmet Sci Chia Nan Univ Pharm & Sci, Inst Cosmet Sci
關鍵字:	anti-aging antioxidant coffee skin
日期:	2021
上傳時間:	2023-11-11 11:48:19 (UTC+8)
出版者:	WILEY
摘要:	Background Coffee and coffee products are known potentially to reduce levels of oxidative stress biomarkers in humans. Objective This investigation evaluates the effects of coffee pulp extract as a functional supplement (in coffee pulp drink, CPD) and a cosmetic ingredient (coffee pulp serum, CPS). Patients/Methods The effects of CPD and CPS for anti-oxidation and anti-aging were investigated. Forty subjects were randomly allocated to CPD or placebo drink groups (50 ml of a CPD/placebo drink daily for 8 weeks for each subject), and another 40 subjects were recruited to CPS or placebo serum groups (about 3 ml of a CPS/placebo serum day and night/daily for 4 weeks for each subject) in a double-blind study. Results The CPD and CPS (20%) can increase free radical scavenging activities by 93.3% and 85% (p < 0.001) for DPPH, 94.5% and 61.3% (p < 0.01) for ABTS center dot(+), 43.8% and 15.3% (p < 0.05) for NO center dot than placebo. The inhibition of tyrosinase activity was increased by 91.6% and 51.0% (p < 0.05) after CPD and CPS application. The CPD comprehensively improved the moisture, brightness, elasticity, spotting, texture, and collagen content of skin for most subjects after 8 weeks, relative to the baseline without treatment (p < 0.05). After 4 weeks of CPS serum consumption, the brightness, elasticity, spotting, UV spots, and collagen content of skin were slightly better than those at week 0 (p < 0.05). Conclusions The daily consumption of coffee pulp extract products can slow the skin aging process and improve skin health.
關聯:	J COSMET DERMATOL-US, v.21, n.5, pp.2189-2199
显示于类别:	[化妝品應用與管理系(所)] 期刊論文

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