Djulis supplementation against oxidative stress and ultraviolet radiation-induced cell damage: The influence of antioxidant status and aging of skin in healthy subjects

doi:10.1111/jocd.14482

Chia Nan University of Pharmacy & Science Institutional Repository > 藥理學院 > 化妝品應用與管理系(所) > 期刊論文 > Item 310902800/34349

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標題:	Djulis supplementation against oxidative stress and ultraviolet radiation-induced cell damage: The influence of antioxidant status and aging of skin in healthy subjects
作者:	Tsai, Tsung-Yi Lin, Rong-Jyh Liu, Cheng Tseng, Ya-Ping Chan, Leong-Perng Liang, Chia-Hua
貢獻者:	Kaohsiung Med Univ, Kaohsiung Municipal TaTung Hosp, Dept Otorhinolaryngol Head & Neck Surg Kaohsiung Med Univ, Coll Med, Fac Med, Dept Otorhinolaryngol Head & Neck Surg Dept Parasitol Grad Inst Med Kaohsiung Med Univ, Coll Med, Sch Med, Dept Med Res Dept Hlth & Beauty Dept Optometry Shu Zen Jr Coll Med & Management, Dept Dent Technol Natl Cheng Kung Univ, Inst Basic Med Sci Chia Nan Univ Pharm & Sci, Dept Cosmet Sci Chia Nan Univ Pharm & Sci, Inst Cosmet Sci
關鍵字:	anti-aging djulis oxidative stress protection skin
日期:	2021
上傳時間:	2023-11-11 11:45:09 (UTC+8)
出版者:	WILEY
摘要:	Background Djulis (Chenopodium formosanum Koidz.) is a cereal food and its antioxidant and pigment constituents may protect skin from photoaging, but conclusive experiments have not been carried out. Objective This investigation evaluates the effects of djulis extract as a functional supplement. Patients/Methods In this study, the effects of djulis functional drinks on the free radical scavenging activities, promotion of collagen synthesis and protection against oxidative stress and the effects of ultraviolet B (UVB)-irradiated of pUC119 DNA were explored. Thirty healthy subjects (aged 35-55 years old) were randomly allocated to djulis or placebo drinks groups (50 ml of a djulis/placebo drink daily for 8 weeks for each subject) in a double-blind crossover study. Results The regular consumption of the djulis functional drinks significantly increased levels of the serum biochemical superoxide dismutase (SOD) and catalase (+9.5% and +124.8%) after 8 weeks, relative to baseline controls. The improvements in skin moisture, brightness, elasticity, crow's feet, texture, wrinkles, pores, and collagen content after 8 weeks in the djulis group were +13.3%, +3.8%, +13.2%, -21.8%, -12.1%, -11.0%, -1.4%, and +33.7%, respectively, relative to the baseline without treatment. Conclusions These work findings suggest the daily consumption of djulis drinks can protect the skin against oxidative stress-induced damage, delay skin aging and improve skin conditions.
關聯:	J COSMET DERMATOL-US, v.21, n.7, pp.2945-2953
显示于类别:	[化妝品應用與管理系(所)] 期刊論文

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