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標題: | 含溫度感應型材料之緩釋型奈米纖維及其製法 Sustained-Release Nanofiber Containing Thermo-Sensitive Material and Method for Making The Same |
作者: | 李佳芬 張羽萱 |
貢獻者: | 化粧品應用與管理系 |
日期: | 2017-04-16 |
上傳時間: | 2021-10-27 16:57:25 (UTC+8) |
摘要: | 本發明係有關於一種含溫度感應型材料之緩釋型奈米纖維及其製法,其製法包括提供複數個乳膠顆粒;將一溫度感應型材料溶解於一甲醇溶液,再加入複數個乳膠顆粒混合,以形成一混合溶液;以及將混合溶液利用靜電紡絲法製成一奈米纖維,並置於110℃進行交聯反應,得到一含溫度感應型材料之緩釋型奈米纖維;所述複數個乳膠顆粒為實心poly(MMA-MAA)/poly(NIPAAm-MAA)乳膠顆粒或空心poly(NIPAAm-MAA)乳膠顆粒。 The invention relates to a sustained-release nanofiber containing a thermo-sensitive material and a method for making the same. The method comprises preparing a plurality of latex particles; dissolving a thermo-sensitive material in a methanol solution and adding the plurality of latex particles to form a mixed solution; and then making the mixed solution into a nanofiber by electrospinning and using a heat-drying way to crosslink the nanofiber at the temperature of?110 ℃, so as to make a sustained-release nanofiber containing the thermo-sensitive material. The plurality of latex particles are solid poly(MMA-MAA)/poly(NIPAAm-MAA) latex particles or hollow poly(NIPAAm-MAA) latex particles. |
關聯: | 專利編號:201713385 申請號:104133725 國際分類號:A61K-009/70(2006.01);A61K-047/32(2006.01) 專利公報:15卷08期 |
顯示於類別: | [化妝品應用與管理系(所)] 專利
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GA-I562802.pdf | | 4260Kb | Adobe PDF | 605 | 檢視/開啟 |
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