Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/32670
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 17744/20032 (89%)
造訪人次 : 7238291      線上人數 : 317
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋
    請使用永久網址來引用或連結此文件: http://ir.cnu.edu.tw/handle/310902800/32670


    標題: Overweight and obesity are associated with clustering of metabolic risk factors in early pregnancy and the risk of GDM
    作者: Yen, I-Weng
    Lee, Chien-Nan
    Lin, Ming-Wei
    Fan, Kang-Chih
    Jung-Nan Wei(魏榮男)
    Chen, Kuan-Yu
    Chen, Szu-Chi
    Tai, Yi-Yun
    Kuo, Chun-Heng
    Lin, Chia-Hung
    Hsu, Chih-Yao
    Chuang, Lee-Ming
    Lin, Shin-Yu
    Li, Hung-Yuan
    貢獻者: Natl Taiwan Univ Hosp, Dept Internal Med, Hsin Chu Branch, Hsinchu, Taiwan
    Natl Taiwan Univ Hosp, Dept Obstet & Gynecol, Taipei, Taiwan
    Chia Nan Univ Pharm & Sci, Tainan, Taiwan
    Ansn Clin, Hsinchu, Taiwan
    Cardinal Tien Hosp, Dept Internal Med, New Taipei, Taiwan
    Fu Jen Catholic Univ Hosp, Dept Internal Med, New Taipei, Taiwan
    Natl Taiwan Univ Hosp, Dept Internal Med, Taipei, Taiwan
    關鍵字: BODY-MASS INDEX
    INSULIN
    INFLAMMATION
    日期: 2019-12
    上傳時間: 2020-07-29 13:54:35 (UTC+8)
    出版者: PUBLIC LIBRARY SCIENCE
    摘要: Aim Overweight and obesity are important risk factors of gestational diabetes mellitus (GDM). Clustering of metabolic risk factors in early pregnancy may be a potential pathogenesis between the link of overweight/obesity and GDM. Since it remains unexplored, we investigated if overweight and obesity are associated with clustering of metabolic risk factors in early pregnancy and the risk of GDM in this cohort study. Methods Total 527 women who visited National Taiwan University Hospital for prenatal care in between November 2013 to April 2018 were enrolled. Risk factors of GDM in the first prenatal visit (FPV) were recorded. Overweight/obesity was defined if body mass index.24 kg/m(2). GDM was diagnosed from the result of a 75g oral glucose tolerance test in 24-28 gestational weeks. Results Overweight/obesity was associated with clustering of metabolic risk factors of GDM, including high fasting plasma glucose, high HbA1c, insulin resistance, high plasma triglyceride and elevated blood pressure in FPV (p< 0.05). There was a positive relationship between the number of metabolic risk factors and the incidence of GDM (p < 0.05). The odds ratios of HbA1c and diastolic blood pressure were higher in overweight/obese women, compared with those in normal-weight women. Conclusions Overweight/obesity is associated with clustering of metabolic risk factors in early pregnancy, which is correlated with higher risk of GDM. Our findings suggest that metabolic risk factors during early pregnancy should be evaluated in overweight/obese women.
    關聯: Plos One, v.14, n.12, e0225978
    顯示於類別:[職業安全衛生系(含防災所)] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    10.1371-journal.pone.0225978.pdf712KbAdobe PDF31檢視/開啟
    index.html0KbHTML37檢視/開啟


    在CNU IR中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋