A New Lipoxygenase Inhibitory Flavonoid from the Kino of Eucalyptus citriodora

Chia Nan University of Pharmacy & Science Institutional Repository > 藥理學院 > 食藥產業暨檢測科技系(含五專) > 期刊論文 > Item 310902800/32577

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標題:	A New Lipoxygenase Inhibitory Flavonoid from the Kino of Eucalyptus citriodora
作者:	Shwu-Woan Lee(李淑婉)
貢獻者:	Chia Nan Univ Pharm & Sci, Dept Med Chem
關鍵字:	Eucalyptus citriodora kino lipoxygenase flavonoid
日期:	2019-01
上傳時間:	2020-07-29 13:50:35 (UTC+8)
出版者:	SPRINGER
摘要:	A new lipoxygenase inhibitory flavonoid, 8-[1-(p-hydroxyphenyl)ethyl]rhamnocitrin (1), together with four known compounds, cinnamic acid (2), p-coumaric acid (3), caffeic acid (4), and gallic acid (5), was isolated from the kino of Eucalyptus citriodora, and their structures were elucidated on the basis of spectroscopic methods including 2D NMR spectra. These compounds were tested for inhibitory activity against 15-lipoxygenase. Compound 1 showed stronger inhibitory activity (IC50 27.6 +/- 0.7 M) than the positive control quercetin (IC50 37.5 +/- 0.8 M).
關聯:	Chemistry of Natural Compounds, v.55, n.1, pp.18-20
顯示於類別:	[食藥產業暨檢測科技系(含五專)] 期刊論文

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