A New Lipoxygenase Inhibitory Flavonoid from the Kino of Eucalyptus citriodora

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Title:	A New Lipoxygenase Inhibitory Flavonoid from the Kino of Eucalyptus citriodora
Authors:	Shwu-Woan Lee(李淑婉)
Contributors:	Chia Nan Univ Pharm & Sci, Dept Med Chem
Keywords:	Eucalyptus citriodora kino lipoxygenase flavonoid
Date:	2019-01
Issue Date:	2020-07-29 13:50:35 (UTC+8)
Publisher:	SPRINGER
Abstract:	A new lipoxygenase inhibitory flavonoid, 8-[1-(p-hydroxyphenyl)ethyl]rhamnocitrin (1), together with four known compounds, cinnamic acid (2), p-coumaric acid (3), caffeic acid (4), and gallic acid (5), was isolated from the kino of Eucalyptus citriodora, and their structures were elucidated on the basis of spectroscopic methods including 2D NMR spectra. These compounds were tested for inhibitory activity against 15-lipoxygenase. Compound 1 showed stronger inhibitory activity (IC50 27.6 +/- 0.7 M) than the positive control quercetin (IC50 37.5 +/- 0.8 M).
Relation:	Chemistry of Natural Compounds, v.55, n.1, pp.18-20
Appears in Collections:	[Dept. of Food & Drug Industry and Inspective Technology] Periodical Articles

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