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| 標題: | Apoptotic and Nonapoptotic Activities of Pterostilbene against Cancer |
| 作者: | Chen, Rong-Jane
Kuo, Hsiao-Che
Cheng, Li-Hsin
Lee, Yu-Hsuan
Chang, Wen-Tsan
Wang, Bour-Jr
Wang, Ying-Jan
Cheng, Hung-Chi |
| 貢獻者: | Natl Cheng Kung Univ, Dept Food Safety Hyg & Risk Management, Coll Med
Natl Cheng Kung Univ, Dept Biochem & Mol Biol, Coll Med
Natl Cheng Kung Univ, Inst Basic Med Sci, Coll Med
Natl Cheng Kung Univ, Dept Environm & Occupat Hlth, Coll Med
Natl Cheng Kung Univ Hosp, Dept Occupat & Environm Med
Chia Nan Univ Pharm & Sci, Dept Cosmet Sci
Chia Nan Univ Pharm & Sci, Inst Cosmet Sci
Taipei Med Univ, Grad Inst Clin Med, Coll Med [Wang, Ying-Jan
China Med Univ, China Med Univ Hosp, Dept Med Res
Asia Univ, Dept Biomed Informat |
| 關鍵字: | apoptosis
fibronectin
cancer metastasis
pterostilbene |
| 日期: | 2018-01 |
| 上傳時間: | 2019-12-16 09:35:44 (UTC+8) |
| 出版者: | MDPI |
| 摘要: | Cancer is a major cause of death. The outcomes of current therapeutic strategies against cancer often ironically lead to even increased mortality due to the subsequent drug resistance and to metastatic recurrence. Alternative medicines are thus urgently needed. Cumulative evidence has pointed out that pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene, PS) has excellent pharmacological benefits for the prevention and treatment for various types of cancer in their different stages of progression by evoking apoptotic or nonapoptotic anti-cancer activities. In this review article, we first update current knowledge regarding tumor progression toward accomplishment of metastasis. Subsequently, we review current literature regarding the anti-cancer activities of PS. Finally, we provide future perspectives to clinically utilize PS as novel cancer therapeutic remedies. We, therefore, conclude and propose that PS is one ideal alternative medicine to be administered in the diet as a nutritional supplement. |
| link: | http://dx.doi.org/10.3390/ijms19010287 |
| 關聯: | International Journal of Molecular Sciences, v.19, n.1, 287 |
| 顯示於類別: | [化妝品應用與管理系(所)] 期刊論文
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