Apoptotic and Nonapoptotic Activities of Pterostilbene against Cancer

doi:10.3390/ijms19010287

CNU IR > Pharmacy and Science > Dept. of Cosmetic Science and institute of cosmetic science > Periodical Articles > Item 310902800/32325

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/32325

Title:	Apoptotic and Nonapoptotic Activities of Pterostilbene against Cancer
Authors:	Chen, Rong-Jane Kuo, Hsiao-Che Cheng, Li-Hsin Lee, Yu-Hsuan Chang, Wen-Tsan Wang, Bour-Jr Wang, Ying-Jan Cheng, Hung-Chi
Contributors:	Natl Cheng Kung Univ, Dept Food Safety Hyg & Risk Management, Coll Med Natl Cheng Kung Univ, Dept Biochem & Mol Biol, Coll Med Natl Cheng Kung Univ, Inst Basic Med Sci, Coll Med Natl Cheng Kung Univ, Dept Environm & Occupat Hlth, Coll Med Natl Cheng Kung Univ Hosp, Dept Occupat & Environm Med Chia Nan Univ Pharm & Sci, Dept Cosmet Sci Chia Nan Univ Pharm & Sci, Inst Cosmet Sci Taipei Med Univ, Grad Inst Clin Med, Coll Med [Wang, Ying-Jan China Med Univ, China Med Univ Hosp, Dept Med Res Asia Univ, Dept Biomed Informat
Keywords:	apoptosis fibronectin cancer metastasis pterostilbene
Date:	2018-01
Issue Date:	2019-12-16 09:35:44 (UTC+8)
Publisher:	MDPI
Abstract:	Cancer is a major cause of death. The outcomes of current therapeutic strategies against cancer often ironically lead to even increased mortality due to the subsequent drug resistance and to metastatic recurrence. Alternative medicines are thus urgently needed. Cumulative evidence has pointed out that pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene, PS) has excellent pharmacological benefits for the prevention and treatment for various types of cancer in their different stages of progression by evoking apoptotic or nonapoptotic anti-cancer activities. In this review article, we first update current knowledge regarding tumor progression toward accomplishment of metastasis. Subsequently, we review current literature regarding the anti-cancer activities of PS. Finally, we provide future perspectives to clinically utilize PS as novel cancer therapeutic remedies. We, therefore, conclude and propose that PS is one ideal alternative medicine to be administered in the diet as a nutritional supplement.
???metadata.dc.relation.uri???:	http://dx.doi.org/10.3390/ijms19010287
Relation:	International Journal of Molecular Sciences, v.19, n.1, 287
Appears in Collections:	[Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles

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