Patterns of failure after postoperative intensity-modulated radiotherapy for locally advanced buccal cancer: Initial masticator space involvement is the key factor of recurrence

doi:10.1002/hed.25355

Chia Nan University of Pharmacy & Science Institutional Repository > 智慧生活學院 > 醫務管理系(所) > 期刊論文 > Item 310902800/32303

請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/32303

標題:	Patterns of failure after postoperative intensity-modulated radiotherapy for locally advanced buccal cancer: Initial masticator space involvement is the key factor of recurrence
作者:	Lin, Yu-Wei Chen, Ya-Fang Yang, Ching-Chieh Ho, Chung-Han Wu, Tai-Ching Yen, Ching-Yu Lin, Li-Ching Lee, Steve P. Lee, Ching-Chih Tai, Ming-Hong
貢獻者:	Chi Mei Med Ctr, Dept Radiat Oncol Natl Sun Yat Sen Univ, Inst Biomed Sci Natl Taiwan Univ Hosp, Dept Med Imaging Chi Mei Med Ctr, Dept Med Res Chia Nan Univ Pharm & Sci, Dept Hosp & Hlth Care Adm Chi Mei Hosp, Dept Radiol Chi Mei Med Ctr, Dept Oral & Maxillofacial Surg Univ Calif Los Angeles, Dept Radiat Oncol Kaohsiung Vet Gen Hosp, Dept Otolaryngol Head & Neck Surg Natl Def Med Ctr, Sch Med Triserv Gen Hosp, Dept Otolaryngol Head & Neck Surg Natl Yang Ming Univ, Inst Hosp & Hlth Care Adm Natl Yang Ming Univ, Sch Med
關鍵字:	adjuvant radiotherapy buccal cancer oral cavity cancer patterns of failure postoperative intensity-modulated radiotherapy (IMRT)
日期:	2018-12
上傳時間:	2019-11-15 15:48:48 (UTC+8)
出版者:	WILEY
摘要:	Background The purpose of this study was to determine failure patterns and clinicopathologic prognostic factors in patients with locally advanced buccal cancer after postoperative intensity-modulated radiotherapy (IMRT). Methods Eighty-two patients with locally advanced (American Joint Committee on Cancer [AJCC] stage III/IV) buccal cancer who underwent surgery followed by postoperative IMRT between January 2007 and October 2012 were retrospectively analyzed. Results Eighteen patients had local recurrences as the first recurrent site and 11 had supramandibular notch recurrences; the majority of recurrences were classified as marginal failures. The median time from the first local or regional recurrence to death was 5.9 months. In multivariate analyses of survivals, the initial masticator space involvement was the most important prognostic factor. Masticator space involvement, N classification, and maxillectomy were the significant prognostic predictors for supramandibular notch recurrences. Conclusion Postoperative IMRT for buccal cancer should not include the surgical beds alone, rather, it should be based on the potential patterns of spread.
link:	http://dx.doi.org/10.1002/hed.25355
關聯:	Journal of Oral Pathology & Medicine, v.40, n.12, pp.2621-2632
顯示於類別:	[醫務管理系(所)] 期刊論文

文件中的檔案:

檔案	描述	大小	格式	瀏覽次數
10.1002-hed.25355.pdf		1091Kb	Adobe PDF	335	檢視/開啟
index.html		0Kb	HTML	1128	檢視/開啟

在CNU IR中所有的資料項目都受到原著作權保護.

TAIR相關文章

資料載入中.....