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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/32241

    標題: Mortality Risks among Various Primary Renal Diseases in Children and Adolescents on Chronic Dialysis
    作者: Chou, Hsin-Hsu
    Chiou, Yuan-Yow
    Chiou, Yee-Hsuan
    Tain, You-Lin
    Wang, Hsin-Hui
    Yu, Mei-Ching
    Hsu, Chih-Cheng
    Lin, Ching-Yuang
    貢獻者: Chia Yi Christian Hosp, Dept Pediat, Ditmanson Med Fdn
    Chia Nan Univ Pharm & Sci, Coll Human Ecol, Dept Appl Life Sci & Hlth
    Natl Cheng Kung Univ, Inst Clin Med, Med Coll & Hosp, Dept Pediat
    Kaohsiung Vet Gen Hosp, Dept Pediat,
    Fooyin Univ, Dept Med Technol
    Chang Gung Mem Hosp, Div Pediat Nephrol, Kaohsiung Med Ctr
    Taipei Vet Gen hosp, Dept Pediat
    Chang Gung Mem Hosp, Div Pediat Nephrol, Linko Med Ctr
    Chang Gung Univ
    Natl Hlth Res Inst, Inst Populat Heath Sci
    Natl Yang Ming Univ, Inst Clin Med
    China Med Univ, Dept Hlth Serv Adm
    China Med Univ, Clin Immunol Ctr, Med Coll & Hosp
    關鍵字: mortality risk
    primary renal disease
    end-stage renal disease
    chronic dialysis
    children and adolescents
    日期: 2018-11
    上傳時間: 2019-11-15 15:46:29 (UTC+8)
    出版者: MDPI
    摘要: There is little information available on the association between primary renal disease (PRD) and long-term mortality in the pediatric dialysis population. The objective of this study was to explore mortality risks in children and adolescents on chronic dialysis, specifically focused on the risk of various PRDs. The study cohort included children and adolescents with end-stage renal disease (ESRD) (aged < 20 years) who had received dialysis for at least 90 days between 2000 and 2014 and were identified from Taiwan's National Health Insurance medical claims. A total of 530 children and adolescents were included in the study. The median age of the included patients was 13.6 years and 305 (57.5%) patients were males. One hundred and seven patients died during the follow-up period and the median survival time was 6.0 years. Mortality was highest in the youngest patients. For patients with the following PRDs, mortality was significantly higher than that in patients with primary glomerulonephritis: secondary glomerulonephritis (adjusted hazard ratio (aHR): 2.50; 95% confidence interval (CI): 1.03-6.08), urologic disorder (aHR: 4.77; 95% CI: 1.69-13.46), and metabolic diseases (aHR: 5.57; 95% CI: 1.84-16.85). Several kinds of PRDs appear to have high mortality risks in the pediatric dialysis population. These differences in mortality risk highlight the importance of the focused clinical management of these high-risk subgroups.
    link: http://dx.doi.org/10.3390/jcm7110414
    關聯: Journal of Clinical Medicine, v.7, n.11, 414
    Appears in Collections:[生活應用與保健系] 期刊論文

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