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https://ir.cnu.edu.tw/handle/310902800/32241
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| 標題: | Mortality Risks among Various Primary Renal Diseases in Children and Adolescents on Chronic Dialysis |
| 作者: | Chou, Hsin-Hsu
Chiou, Yuan-Yow
Chiou, Yee-Hsuan
Tain, You-Lin
Wang, Hsin-Hui
Yu, Mei-Ching
Hsu, Chih-Cheng
Lin, Ching-Yuang |
| 貢獻者: | Chia Yi Christian Hosp, Dept Pediat, Ditmanson Med Fdn
Chia Nan Univ Pharm & Sci, Coll Human Ecol, Dept Appl Life Sci & Hlth
Natl Cheng Kung Univ, Inst Clin Med, Med Coll & Hosp, Dept Pediat
Kaohsiung Vet Gen Hosp, Dept Pediat,
Fooyin Univ, Dept Med Technol
Chang Gung Mem Hosp, Div Pediat Nephrol, Kaohsiung Med Ctr
Taipei Vet Gen hosp, Dept Pediat
Chang Gung Mem Hosp, Div Pediat Nephrol, Linko Med Ctr
Chang Gung Univ
Natl Hlth Res Inst, Inst Populat Heath Sci
Natl Yang Ming Univ, Inst Clin Med
China Med Univ, Dept Hlth Serv Adm
China Med Univ, Clin Immunol Ctr, Med Coll & Hosp |
| 關鍵字: | mortality risk
primary renal disease
end-stage renal disease
chronic dialysis
children and adolescents |
| 日期: | 2018-11 |
| 上傳時間: | 2019-11-15 15:46:29 (UTC+8) |
| 出版者: | MDPI |
| 摘要: | There is little information available on the association between primary renal disease (PRD) and long-term mortality in the pediatric dialysis population. The objective of this study was to explore mortality risks in children and adolescents on chronic dialysis, specifically focused on the risk of various PRDs. The study cohort included children and adolescents with end-stage renal disease (ESRD) (aged < 20 years) who had received dialysis for at least 90 days between 2000 and 2014 and were identified from Taiwan's National Health Insurance medical claims. A total of 530 children and adolescents were included in the study. The median age of the included patients was 13.6 years and 305 (57.5%) patients were males. One hundred and seven patients died during the follow-up period and the median survival time was 6.0 years. Mortality was highest in the youngest patients. For patients with the following PRDs, mortality was significantly higher than that in patients with primary glomerulonephritis: secondary glomerulonephritis (adjusted hazard ratio (aHR): 2.50; 95% confidence interval (CI): 1.03-6.08), urologic disorder (aHR: 4.77; 95% CI: 1.69-13.46), and metabolic diseases (aHR: 5.57; 95% CI: 1.84-16.85). Several kinds of PRDs appear to have high mortality risks in the pediatric dialysis population. These differences in mortality risk highlight the importance of the focused clinical management of these high-risk subgroups. |
| link: | http://dx.doi.org/10.3390/jcm7110414 |
| 關聯: | Journal of Clinical Medicine, v.7, n.11, 414 |
| 顯示於類別: | [生活保健科技系] 期刊論文
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