Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/32191
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    標題: Development and characterization of a green procedure for apigenin extraction from Scutellaria barbata D. Don
    作者: Yang, Yu-Chiao
    Wei, Ming-Chi
    貢獻者: Kaohsiung Med Univ, Dept & Grad Inst Pharmacol
    Kaohsiung Med Univ Hosp, Dept Med Res
    Chia Nan Univ Pharm & Sci, Dept Appl Geoinformat
    關鍵字: Scutellaria barbata D. Don
    Apigenin
    Supercritical CO2 extraction
    Ultrasound-assisted extraction
    Second-order kinetic model
    Eyring transition state theory
    Green alternative procedure
    Theoretical solubility
    日期: 2018-06-30
    上傳時間: 2019-11-15 15:44:30 (UTC+8)
    出版者: ELSEVIER SCI LTD
    摘要: This study compared the use of ultrasound-assisted supercritical CO2 (USC-CO2) extraction to obtain apigenin-rich extracts from Scutellaria barbata D. Don with that of conventional supercritical CO2 (SC-CO2) extraction and heat-reflux extraction (HRE), conducted in parallel. This green procedure yielded 20.1% and 31.6% more apigenin than conventional SC-CO2 extraction and HRE, respectively. Moreover, the extraction time required by the USC-CO2 procedure, which used milder conditions, was approximately 1.9 times and 2.4 times shorter than that required by conventional SC-CO2 extraction and HRE, respectively. Furthermore, the theoretical solubility of apigenin in the supercritical fluid system was obtained from the USC-CO2 dynamic extraction curves and was in good agreement with the calculated values for the three empirical density-based models. The second-order kinetics model was further applied to evaluate the kinetics of USC-CO2 extraction. The results demonstrated that the selected model allowed the evaluation of the extraction rate and extent of USC-CO2 extraction.
    link: http://dx.doi.org/10.1016/j.foodchem.2017.12.086
    關聯: Nonlinear Analysis-Hybrid Systems, v.252, pp.381-389
    显示于类别:[應用空間資訊系(所)] 期刊論文

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