| Title: | Development and characterization of a green procedure for apigenin extraction from Scutellaria barbata D. Don |
| Authors: | Yang, Yu-Chiao
Wei, Ming-Chi |
| Contributors: | Kaohsiung Med Univ, Dept & Grad Inst Pharmacol
Kaohsiung Med Univ Hosp, Dept Med Res
Chia Nan Univ Pharm & Sci, Dept Appl Geoinformat |
| Keywords: | Scutellaria barbata D. Don
Apigenin
Supercritical CO2 extraction
Ultrasound-assisted extraction
Second-order kinetic model
Eyring transition state theory
Green alternative procedure
Theoretical solubility |
| Date: | 2018-06-30 |
| Issue Date: | 2019-11-15 15:44:30 (UTC+8) |
| Publisher: | ELSEVIER SCI LTD |
| Abstract: | This study compared the use of ultrasound-assisted supercritical CO2 (USC-CO2) extraction to obtain apigenin-rich extracts from Scutellaria barbata D. Don with that of conventional supercritical CO2 (SC-CO2) extraction and heat-reflux extraction (HRE), conducted in parallel. This green procedure yielded 20.1% and 31.6% more apigenin than conventional SC-CO2 extraction and HRE, respectively. Moreover, the extraction time required by the USC-CO2 procedure, which used milder conditions, was approximately 1.9 times and 2.4 times shorter than that required by conventional SC-CO2 extraction and HRE, respectively. Furthermore, the theoretical solubility of apigenin in the supercritical fluid system was obtained from the USC-CO2 dynamic extraction curves and was in good agreement with the calculated values for the three empirical density-based models. The second-order kinetics model was further applied to evaluate the kinetics of USC-CO2 extraction. The results demonstrated that the selected model allowed the evaluation of the extraction rate and extent of USC-CO2 extraction. |
| ???metadata.dc.relation.uri???: | http://dx.doi.org/10.1016/j.foodchem.2017.12.086 |
| Relation: | Nonlinear Analysis-Hybrid Systems, v.252, pp.381-389 |
| Appears in Collections: | [Dept. of Applied Geoinformatics] Periodical Articles
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