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    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/32169

    標題: Pregnancy outcomes following nonobstetric surgery during gestation: a nationwide population-based case-control study in Taiwan
    作者: Yu, Chia-Hung
    Weng, Shih-Feng
    Ho, Chung-Han
    Chen, Yi-Chen
    Chen, Jen-Yin
    Chang, Ying-Jen
    Wang, Jhi-Joung
    Wu, Ming-Ping
    Chu, Chin-Chen
    貢獻者: Chi Mei Med Ctr, Div Womens & Childrens Anesthesia, Dept Anesthesiol
    Kaohsiung Med Univ, Dept Healthcare Adm & Med Informat
    Chi Mei Med Ctr, Dept Med Res
    Chia Nan Univ Pharm & Sci, Dept Pharm, Chi Mei Med Ctr
    Chia Nan Univ Pharm & Sci, Dept Senior Citizen Serv Management, Chi Mei Med Ctr
    Chi Mei Med Ctr, Div Urogynecol & Pelv Floor Reconstruct, Dept Obstet & Gynecol
    Chia Nan Univ Pharm & Sci, Ctr Gen Educ, Chi Mei Med Ctr
    關鍵字: Pregnancy
    Nonobstetric surgery
    Delivery outcome
    日期: 2018-11-26
    上傳時間: 2019-11-15 15:43:34 (UTC+8)
    出版者: BMC
    摘要: BackgroundWhether nonobstetric surgery during gestation is associated with a higher risk of spontaneous abortion or adverse delivery outcomes is still unclear.MethodsWe performed a retrospective case-control study using a Longitudinal Health Insurance Database (LHID 2000) containing claim-data of 1 million randomly selected beneficiaries. We compared the incidences and estimated the adjusted odds ratios (aOR) with 95% confidence interval (95% CI) for spontaneous abortion, adverse delivery outcomes, cesarean delivery, and prolonged hospital stay to determine the risk of adverse outcomes in women who had nonobstetric surgery during gestation as compared to those who did not have any surgery during gestation.ResultsAfter exclusion, we were left with 114,852 delivery and 3999 abortion cases in our study; and 462 (0.39%) of them had nonobstetric surgery under general or regional anesthesia during pregnancy. The leading surgeries were repair of cervical os (33.12%), appendectomy (17.32%), ovarian surgeries (13.64%), and fixation of fractured bone (8.01%).The risk of spontaneous abortion (4.23% vs. 2.43%, aOR:1.53; 95% CI: 1.01-2.31), antepartum hemorrhage (7.14% vs. 2.83%, aOR: 2.51; 95% CI: 1.74-3.61), pre-eclampsia/eclampsia (2.60% vs. 1.01%, aOR: 2.35; 95% CI: 1.30-4.23), gestational diabetes (2.38% vs. 0.69%, aOR: 3.12; 95% CI: 1.69-5.78), prematurity (9.06 vs. 4.90%, aOR: 3.31; 95% CI: 2.54-4.31), cesarean section (43.55% vs. 33.76%, aOR: 1.41; 95% CI: 1.17-1.71), and prolonged hospital stay (1.82% vs. 5.91%, aOR: 3.23; 95% CI: 2.16-4.83) were higher in those women who had nonobstetric surgery after adjusting for age and comorbidities.ConclusionsNonobstetric surgery during gestation were associated with a higher risk of spontaneous abortion, adverse delivery outcomes, cesarean section, and prolonged hospital stay.
    link: http://dx.doi.org/10.1186/s12884-018-2079-4
    關聯: Bmc Nephrology, v.18, 460
    Appears in Collections:[藥學系(所)] 期刊論文
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