Pregnancy outcomes following nonobstetric surgery during gestation: a nationwide population-based case-control study in Taiwan

doi:10.1186/s12884-018-2079-4

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Title:	Pregnancy outcomes following nonobstetric surgery during gestation: a nationwide population-based case-control study in Taiwan
Authors:	Yu, Chia-Hung Weng, Shih-Feng Ho, Chung-Han Chen, Yi-Chen Chen, Jen-Yin Chang, Ying-Jen Wang, Jhi-Joung Wu, Ming-Ping Chu, Chin-Chen
Contributors:	Chi Mei Med Ctr, Div Womens & Childrens Anesthesia, Dept Anesthesiol Kaohsiung Med Univ, Dept Healthcare Adm & Med Informat Chi Mei Med Ctr, Dept Med Res Chia Nan Univ Pharm & Sci, Dept Pharm, Chi Mei Med Ctr Chia Nan Univ Pharm & Sci, Dept Senior Citizen Serv Management, Chi Mei Med Ctr Chi Mei Med Ctr, Div Urogynecol & Pelv Floor Reconstruct, Dept Obstet & Gynecol Chia Nan Univ Pharm & Sci, Ctr Gen Educ, Chi Mei Med Ctr
Keywords:	Pregnancy Nonobstetric surgery Abortion Delivery outcome
Date:	2018-11-26
Issue Date:	2019-11-15 15:43:34 (UTC+8)
Publisher:	BMC
Abstract:	BackgroundWhether nonobstetric surgery during gestation is associated with a higher risk of spontaneous abortion or adverse delivery outcomes is still unclear.MethodsWe performed a retrospective case-control study using a Longitudinal Health Insurance Database (LHID 2000) containing claim-data of 1 million randomly selected beneficiaries. We compared the incidences and estimated the adjusted odds ratios (aOR) with 95% confidence interval (95% CI) for spontaneous abortion, adverse delivery outcomes, cesarean delivery, and prolonged hospital stay to determine the risk of adverse outcomes in women who had nonobstetric surgery during gestation as compared to those who did not have any surgery during gestation.ResultsAfter exclusion, we were left with 114,852 delivery and 3999 abortion cases in our study; and 462 (0.39%) of them had nonobstetric surgery under general or regional anesthesia during pregnancy. The leading surgeries were repair of cervical os (33.12%), appendectomy (17.32%), ovarian surgeries (13.64%), and fixation of fractured bone (8.01%).The risk of spontaneous abortion (4.23% vs. 2.43%, aOR:1.53; 95% CI: 1.01-2.31), antepartum hemorrhage (7.14% vs. 2.83%, aOR: 2.51; 95% CI: 1.74-3.61), pre-eclampsia/eclampsia (2.60% vs. 1.01%, aOR: 2.35; 95% CI: 1.30-4.23), gestational diabetes (2.38% vs. 0.69%, aOR: 3.12; 95% CI: 1.69-5.78), prematurity (9.06 vs. 4.90%, aOR: 3.31; 95% CI: 2.54-4.31), cesarean section (43.55% vs. 33.76%, aOR: 1.41; 95% CI: 1.17-1.71), and prolonged hospital stay (1.82% vs. 5.91%, aOR: 3.23; 95% CI: 2.16-4.83) were higher in those women who had nonobstetric surgery after adjusting for age and comorbidities.ConclusionsNonobstetric surgery during gestation were associated with a higher risk of spontaneous abortion, adverse delivery outcomes, cesarean section, and prolonged hospital stay.
???metadata.dc.relation.uri???:	http://dx.doi.org/10.1186/s12884-018-2079-4
Relation:	Bmc Nephrology, v.18, 460
Appears in Collections:	[Dept. of Pharmacy] Periodical Articles [Dept. of Senior Service and Health Management] Periodical Articles [The Center For General Education] Periodical Articles

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