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| 標題: | One-Year Mortality of Patients with Chronic Kidney Disease After Spinal Cord Injury: A 14-Year Population-Based Study |
| 作者: | Yu, Shou-Chun
Kuo, Jinn-Rung
Shiue, Yow-Ling
Yu, Zong-Xing
Ho, Chung-Han
Wu, Chia-Chun
Wang, Jhi-Joung
Chu, Chin-Chen
Lim, Sher-Wei |
| 關鍵字: | Chronic kidney disease
End-stage renal disease
Mortality
Population-based study
Spinal cord injury
Taiwan |
| 日期: | 2017-09 |
| 上傳時間: | 2018-11-30 15:57:12 (UTC+8) |
| 出版者: | Elsevier Science Inc |
| 摘要: | OBJECTIVE: Chronic kidney disease (CKD) has become a global public health burden because of its increasing incidence, high risk of progression to end-stage renal disease (ESRD), and poor prognosis. We aimed to investigate the 1-year mortality of patients with spinal cord injury (SCI) with CKD and ESRD, and compare it with that of patients with SCI without CKD by reviewing a large Taiwanese population data set. METHODS: In this 14-year retrospective cohort study, the study group (SCI with CKD group, n = 3315) and comparison group (SCI without CKD group, n = 6630) were matched at a 1: 2 ratio with propensity score matching by age, sex, comorbidities, length of intensive care unit stay, and length of stay. The 1-year mortality and the relative risks of mortality were calculated. Mortality stratified by age, sex, and comorbidities was also analyzed. RESULTS: The SCI with CKD group had a significantly shorter survival period (10.13 vs. 10.97 months), higher 1-year mortality (17.65% vs. 8.54%), and higher risk of mortality than did the comparison group (adjusted hazard ratio, 2.25). Furthermore, patients with CKD with ESRD had a 7.71-fold higher risk of mortality than did patients with SCI without CKD for ages < 50 years. The presence of comorbidities was a risk factor for mortality among patients with SCI CKD or ESRD in contrast to patients with SCI without CKD. CONCLUSIONS: Patients with SCI with CKD, especially those with ESRD, have a higher risk of mortality than do patients who do not have CKD. Therefore, patients with CKD should have carefully monitoring for the development of 1-year mortality after SCI, especially for ESRD. |
| 關聯: | World Neurosurgery, v.105, pp.462-469 |
| 顯示於類別: | [藥學系(所)] 期刊論文
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