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| 標題: | Establishing failure predictors for the planned extubation of overweight and obese patients |
| 作者: | Chao, Chien-Ming
Lai, Chih-Cheng
Cheng, Ai-Chin
Chiang, Shyh-Ren
Liu, Wei-Lun
Ho, Chung-Han
Hsing, Shu-Chen
Chen, Chin-Ming
Cheng, Kuo-Chen |
| 貢獻者: | Chi Mei Med Ctr, Dept Intens Care Med
Chi Mei Med Ctr, Dept Internal Med
Chia Nan Univ Pharm & Sci
Chi Mei Med Ctr, Dept Med Res
Chi Mei Med Ctr, Dept Intens Care Med
Chung Hwa Univ Med Technol, Dept Safety Hlth & Environm Engn |
| 關鍵字: | Intensive-Care-Unit
Spontaneous Breathing Trial
Mechanical Ventilation
Cardiovascular-Disease
Bariatric Surgery
Mortality
Outcomes
Cohort
Parameters
Model |
| 日期: | 2017-08-16 |
| 上傳時間: | 2018-11-30 15:55:54 (UTC+8) |
| 出版者: | Public Library Science |
| 摘要: | We investigated failure predictors for the planned extubation of overweight (body mass index [BMI] = 25.0-29.9) and obese (BMI >= 30) patients. All patients admitted to the adult intensive care unit (ICU) of a tertiary hospital in Taiwan were identified. They had all undergone endotracheal intubation for > 48 h and were candidates for extubation. During the study, 595 patients (overweight = 458 [77%]); obese = 137 [23%]) with planned extubation after weaning were included in the analysis; extubation failed in 34 patients (5.7%). Their mean BMI was 28.5 +/- 3.8. Only BMI and age were significantly different between overweight and obese patients. The mortality rate for ICU patients was 0.8%, and 2.9% for inpatients during days 1-28; the overall in- hospital mortality rate was 8.4%. Failed Extubation group patients were significantly older, had more end- stage renal disease (ESRD), more cardiovascular system- related respiratory failure, higher maximal inspiratory pressure (MIP), lower maximal expiratory pressure (MEP), higher blood urea nitrogen, and higher ICU- and 28-day mortality rates than did the Successful Extubation group. Multivariate logistic regression showed that cardiovascular- related respiratory failure (odds ratio [OR]: 2.60; 95% [confidence interval] CI: 1.16-5.80), ESRD (OR: 14.00; 95% CI: 6.25-31.35), and MIP levels (OR: 0.94; 95% CI: 0.90-0.97) were associated with extubation failure. We conclude that the extubation failure risk in overweight and obese patients was associated with cardiovascular system- related respiratory failure, ESRD, and low MIP levels. |
| 關聯: | Plos One, v.12, n.8, e0183360 |
| 顯示於類別: | [應用外語系] 科技部計畫
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