English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 18034/20233 (89%)
造訪人次 : 23351470      線上人數 : 454
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋
    請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/31069


    標題: Asthma-Chronic Obstructive Pulmonary Diseases Overlap Syndrome Increases the Risk of Incident Tuberculosis: A National Cohort Study
    作者: Yeh, Jun-Jun
    Wang, Yu-Chiao
    Kao, Chia-Hung
    貢獻者: Chia Yi Christian Hosp, Ditmanson Med Fdn
    Chia Nan Univ Pharm & Sci
    Meiho Univ
    China Med Univ Hosp, Management Off Hlth Data
    China Med Univ, Coll Med
    China Med Univ, Coll Med, Grad Inst Clin Med Sci
    China Med Univ Hosp, Dept Nucl Med
    China Med Univ Hosp, PET Ctr
    關鍵字: copd overlap
    inhaled corticosteroids
    syndrome acos
    lung-disease
    taiwan
    exacerbations
    tiotropium
    phenotypes
    stay
    gold
    日期: 2016-07
    上傳時間: 2018-01-18 11:41:03 (UTC+8)
    出版者: Public Library Science
    摘要: Purpose The association between asthma-chronic obstructive pulmonary diseases (COPD) overlap syndrome (ACOS) and tuberculosis (TB) has yet to be studied. Methods The newly diagnosed TB patients (age > 20 y) treated from January 2000 to December 2008 were included (ACOS cohort, n = 10 751; non-ACOS cohort, n = 42 966). The non-ACOS cohort involved patients with confirmed absence of ACOS. We calculated incidence rate ratios (IRRs) for TB in the ACOS and non-ACOS cohorts by using poisson regression analysis. Cox proportional hazards regression models were used to determine the adjusted HR (aHR) for TB in the ACOS cohort compared with the non-ACOS cohort. Results The aHR for TB was 2.41 (95% confidence interval [CI], 2.19-2.66) in the ACOS cohort. The TB risk was significantly higher in the ACOS cohort than in the non-ACOS cohort when stratified by age, sex, comorbidities, and atopy. Within the ACOS cohort, the aHR was higher among patients receiving SABAs+ SAMAs, LABAs+ LAMAs, and ICSs (aHR [95% CI]: 3.06 [2.75-3.41], 3.68 [2.93-4.61], and 2.79 [1.25-6.22], respectively; all P <.05). Furthermore, patients with more than 15 outpatient visits and hospitalizations per year demonstrated the highest aHR (8.09; 95% CI, 6.85-9.56). Conclusions ACOS cohort potentially develop incident TB, regardless of the age, sex, comorbidities and atopy; even without receiving the inhalers. This risk is higher, especially in the ACOS cohort have a high frequency of medical services or receiving the inhalers such as SABAs +SAMAs, LABAs+LAMAs and ICSs.
    關聯: Plos One, v.11 n.7, e0159012
    顯示於類別:[嬰幼兒保育系] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    31069.pdf387KbAdobe PDF320檢視/開啟
    index.html0KbHTML1484檢視/開啟


    在CNU IR中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋