Architecture effects of glucose oxidase/Au nanoparticle composite Langmuir-Blodgett films on glucose sensing performance

doi:10.1016/j.apsusc.2016.01.047

CNU IR > Pharmacy and Science > Dept. of Food & Drug Industry and Inspective Technology > Periodical Articles > Item 310902800/31023

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/31023

Title:	Architecture effects of glucose oxidase/Au nanoparticle composite Langmuir-Blodgett films on glucose sensing performance
Authors:	Wang, Ke-Hsuan Wu, Jau-Yann Chen, Liang-Huei Lee, Yuh-Lang
Contributors:	Natl Cheng Kung Univ, Dept Chem Engn I Shou Univ, Dept Chem Engn Chia Nan Univ Pharm & Sci, Dept Med Chem
Keywords:	Langmuir-Blodgett films Glucose oxidase Gold nanoparticles Composite film Architecture effect immobilization
Date:	2016-03
Issue Date:	2018-01-18 11:40:03 (UTC+8)
Publisher:	Elsevier Science Bv
Abstract:	The Langmuir-Blodgett (LB) deposition technique is employed to prepare nano-composite films consisting of glucose oxidase (GOx) and gold nanoparticles (AuNPs) for glucose sensing applications. The GOx and AuNPs are co-adsorbed from an aqueous solution onto an air/liquid interface in the presence of an octadecylamine ( ODA) template monolayer, forming a mixed (GOx-AuNP) monolayer. Alternatively, a composite film with a cascade architecture (AuNP/G0x) is also prepared by sequentially depositing monolayers of AuNPs and GOx. The architecture effects of the composite LB films on the glucose sensing are studied. The results show that the presence of AuNPs in the co-adsorption system does not affect the adsorption amount and preferred conformation (alpha-helix) of GOx. Furthermore, the incorporation of AuNPs in both composite films can significantly improve the sensing performance. However, the enhancement effects of the AuNPs in the two architectures are distinct. The major effect of the AuNPs is on the facilitation of charge-transfer in the (GOx-AuNP) film, but on the increase of catalytic activity in the (AuNP/G0x) one. Therefore, the sensing performance can be greatly improved by utilizing a film combining both architectures (AuNP/G0x-AuNP). (C) 2016 Elsevier B.V. All rights reserved.
Relation:	Applied Surface Science, v.366, pp.202-209
Appears in Collections:	[Dept. of Food & Drug Industry and Inspective Technology] Periodical Articles

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