Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/29763
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    標題: Risk of retinal vein occlusion in patients with psoriasis a population-based cohort study
    作者: Yen, Yung-Chang
    Weng, Shih-Feng
    Lai, Feng-Jie
    Lin, Yung-Song
    貢獻者: 醫務管理系
    關鍵字: systemic-lupus-erythematosus
    retinal vein occlusion
    psoriasis
    autoimmune disease
    日期: 2015-09
    上傳時間: 2016-04-19 19:07:18 (UTC+8)
    出版者: Lippincott Williams & Wilkins
    摘要: Purpose:
    To investigate the risk of developing retinal vein occlusion (RVO) in patients with psoriasis.
    Methods:
    In this retrospective population-based cohort study, 30,198 patients with psoriasis (Psoriasis((+)) group) and 30,198 controls without psoriasis (Psoriasis((-)) group) between 2001 and 2006 from the Taiwan National Health Insurance Research Database were selected.
    Results:
    The incidence of RVO was 1.46 times higher in the Psoriasis((+)) group than in the Psoriasis((-)) group (3.61 vs. 2.47/10,000 person-years) (adjusted hazard ratio = 1.50; 95% confidence interval = 1.07-2.10) calculated using Cox proportional hazard regression. Age was an independent risk factor for RVO (adjusted hazard ratio: 11.9 for patients 65 years or older vs. 1.00 for those 0-49 years old). In the 65 years or older Psoriasis((+)) group, the incidence of developing RVO was 1.97 times higher (95% confidence interval = 1.19-3.26) than in the 65 years or older Psoriasis((-)) group. In Psoriasis((+)) women, the incidence of developing RVO was 1.82 times higher (95% = 1.05-3.14) than in Psoriasis((-)) women. For the subgroup with comorbid hypertension, the incidence of developing RVO was 2.07 times higher (95% confidence interval = 1.22-3.50) in the Psoriasis((+)) group than in the Psoriasis((-)) group.
    Conclusion:
    Psoriasis was significantly associated with a higher risk of developing RVO.
    關聯: Retina-The Journal of Retinal And Vitreous Diseases, v.35 n.9, pp.1786-1794
    顯示於類別:[醫務管理系(所)] 期刊論文

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