Risk of retinal vein occlusion in patients with psoriasis a population-based cohort study

doi:10.1097/IAE.0000000000000536

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Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/29763

Title:	Risk of retinal vein occlusion in patients with psoriasis a population-based cohort study
Authors:	Yen, Yung-Chang Weng, Shih-Feng Lai, Feng-Jie Lin, Yung-Song
Contributors:	醫務管理系
Keywords:	systemic-lupus-erythematosus retinal vein occlusion psoriasis autoimmune disease
Date:	2015-09
Issue Date:	2016-04-19 19:07:18 (UTC+8)
Publisher:	Lippincott Williams & Wilkins
Abstract:	Purpose: To investigate the risk of developing retinal vein occlusion (RVO) in patients with psoriasis. Methods: In this retrospective population-based cohort study, 30,198 patients with psoriasis (Psoriasis((+)) group) and 30,198 controls without psoriasis (Psoriasis((-)) group) between 2001 and 2006 from the Taiwan National Health Insurance Research Database were selected. Results: The incidence of RVO was 1.46 times higher in the Psoriasis((+)) group than in the Psoriasis((-)) group (3.61 vs. 2.47/10,000 person-years) (adjusted hazard ratio = 1.50; 95% confidence interval = 1.07-2.10) calculated using Cox proportional hazard regression. Age was an independent risk factor for RVO (adjusted hazard ratio: 11.9 for patients 65 years or older vs. 1.00 for those 0-49 years old). In the 65 years or older Psoriasis((+)) group, the incidence of developing RVO was 1.97 times higher (95% confidence interval = 1.19-3.26) than in the 65 years or older Psoriasis((-)) group. In Psoriasis((+)) women, the incidence of developing RVO was 1.82 times higher (95% = 1.05-3.14) than in Psoriasis((-)) women. For the subgroup with comorbid hypertension, the incidence of developing RVO was 2.07 times higher (95% confidence interval = 1.22-3.50) in the Psoriasis((+)) group than in the Psoriasis((-)) group. Conclusion: Psoriasis was significantly associated with a higher risk of developing RVO.
Relation:	Retina-The Journal of Retinal And Vitreous Diseases, v.35 n.9, pp.1786-1794
Appears in Collections:	[Dept. of Hospital and Health (including master's program)] Periodical Articles

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