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| 標題: | Epidemiologic features and long-term outcome of dialysis patients with infective endocarditis in Taiwan |
| 作者: | Chou, Ming-Ting
Wang, Jhi-Joung
Wu, Wen-Shiann
Weng, Shih-Feng
Ho, Chung-Han
Lin, Zhe-Zhong
Cheng, Tain-Junn
Chien, Chih-Chiang |
| 貢獻者: | 通識教育中心
醫務管理系
職業安全衛生系 |
| 關鍵字: | Infective endocarditis
Rheumatic heart disease
Dialysis |
| 日期: | 2015-01 |
| 上傳時間: | 2016-04-19 19:05:47 (UTC+8) |
| 出版者: | Elsevier Ireland Ltd |
| 摘要: | Background: The incidence of infective endocarditis (IE) is high in dialysis patients. Limited data are available on the risk factors for IE and long-term outcome after IE in dialysis patients, especially in Asian populations.
Methods: We used Taiwan National Health Insurance Research Database to design a longitudinal cohort study. 68,426 ESRD patients who began dialysis between 1999 and 2007 were included. The follow-up period was from the start of dialysis to death, end of dialysis, or end of 2008. Cox proportional hazards models were used to identify the risk factors for IE.
Results: IE was diagnosed in 502 patients during follow-up (201.4 per 100,000 person-years). Diabetes mellitus (DM), congestive heart failure (CHF), cerebro-vascular accident (CVA), and rheumatic heart disease (RHD) (HR: 3.07, 95% CI: 1.99-4.75) were associated with an increasing risk of development of IE. The cumulative incidence rate of IE in patients with RHD was 1.4, 2.2, and 3.9% at 1, 3, and 5 years. In-hospital mortality was 23.5%. Cumulative survival rates post-IE were 54.3% at 1 year and only 35.3% at 5 years.
Conclusion: Dialysis patients had a higher risk of IE. Those who were older and had DM, CHF, CVA, or especially RHD were at a greater risk. Dialysis patients with IE also had high mortality |
| 關聯: | International Journal of Cardiology, v.179, pp.465-469 |
| 顯示於類別: | [職業安全衛生系(含防災所)] 期刊論文
[醫務管理系(所)] 期刊論文
[通識教育中心] 期刊論文
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