Epidemiologic features and long-term outcome of dialysis patients with infective endocarditis in Taiwan

doi:10.1016/j.ijcard.2014.11.083

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Title:	Epidemiologic features and long-term outcome of dialysis patients with infective endocarditis in Taiwan
Authors:	Chou, Ming-Ting Wang, Jhi-Joung Wu, Wen-Shiann Weng, Shih-Feng Ho, Chung-Han Lin, Zhe-Zhong Cheng, Tain-Junn Chien, Chih-Chiang
Contributors:	通識教育中心醫務管理系職業安全衛生系
Keywords:	Infective endocarditis Rheumatic heart disease Dialysis
Date:	2015-01
Issue Date:	2016-04-19 19:05:47 (UTC+8)
Publisher:	Elsevier Ireland Ltd
Abstract:	Background: The incidence of infective endocarditis (IE) is high in dialysis patients. Limited data are available on the risk factors for IE and long-term outcome after IE in dialysis patients, especially in Asian populations. Methods: We used Taiwan National Health Insurance Research Database to design a longitudinal cohort study. 68,426 ESRD patients who began dialysis between 1999 and 2007 were included. The follow-up period was from the start of dialysis to death, end of dialysis, or end of 2008. Cox proportional hazards models were used to identify the risk factors for IE. Results: IE was diagnosed in 502 patients during follow-up (201.4 per 100,000 person-years). Diabetes mellitus (DM), congestive heart failure (CHF), cerebro-vascular accident (CVA), and rheumatic heart disease (RHD) (HR: 3.07, 95% CI: 1.99-4.75) were associated with an increasing risk of development of IE. The cumulative incidence rate of IE in patients with RHD was 1.4, 2.2, and 3.9% at 1, 3, and 5 years. In-hospital mortality was 23.5%. Cumulative survival rates post-IE were 54.3% at 1 year and only 35.3% at 5 years. Conclusion: Dialysis patients had a higher risk of IE. Those who were older and had DM, CHF, CVA, or especially RHD were at a greater risk. Dialysis patients with IE also had high mortality
Relation:	International Journal of Cardiology, v.179, pp.465-469
Appears in Collections:	[Dept. of Occupational Safety] Periodical Articles [Dept. of Hospital and Health (including master's program)] Periodical Articles [The Center For General Education] Periodical Articles

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