Differences between novel and conventional surveillance paradigms of ventilator-associated pneumonia

doi:10.1016/j.ajic.2014.10.029

Chia Nan University of Pharmacy & Science Institutional Repository > 環境永續暨休閒學院 > 休閒保健管理系(所) > 期刊論文 > Item 310902800/29707

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標題:	Differences between novel and conventional surveillance paradigms of ventilator-associated pneumonia
作者:	Chang, Hui-Chun Chen, Chin-Ming Kung, Shu-Chen Wang, Ching-Min Liu, Wei-Lun Lai, Chih-Cheng
貢獻者:	休閒保健管理系
關鍵字:	Ventilator-associated event Diagnosis Definition
日期:	2015-02
上傳時間:	2016-04-19 19:05:21 (UTC+8)
出版者:	Mosby-Elsevier
摘要:	Objective: To investigate the concordance between novel and conventional surveillance paradigms for ventilator-associated pneumonia (VAP). Methods: This study was conducted at a regional teaching hospital in southern Taiwan with 5 acute intensive care units. To assess the validity of novel ventilator-associated event (VAE) surveillance, we retrospectively applied the VAE algorithm to analyze all VAP cases that were identified using conventional definitions between April 2010 and February 2014. Patient outcomes, including ventilator days, hospital stay lengths, and in-hospital mortality were recorded. Results: Among 165 episodes of conventional VAP, 55 (33.3%), 40 (24.2%), 20 (12.1%), and 2 (1.2%) episodes were classified as a ventilator-associated condition, an infection-related ventilator-associated complication, possible VAP, and probable VAP, respectively, according to the new VAE algorithm. Changes in positive end-expiratory pressure and inspired oxygen fraction levels during the development of VAP were significant higher among each VAE category than for conventional VAP (all P < .001). In-hospital mortality was significantly higher among patients with ventilator-associated condition than for patients with conventional VAP (P = .0185). Conclusions: In our study population, novel VAE surveillance only detected one-third of conventional VAP cases. Thus, more studies are needed to further validate VAE surveillance compared with conventional VAP by using strong microbiologic criteria, particularly bronchoalveolar lavage with a protected specimen brush for diagnosing VAP
關聯:	American Journal of Infection Control, v.43 n.2, pp.133-136
显示于类别:	[休閒保健管理系(所)] 期刊論文

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