Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/29707
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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/29707


    Title: Differences between novel and conventional surveillance paradigms of ventilator-associated pneumonia
    Authors: Chang, Hui-Chun
    Chen, Chin-Ming
    Kung, Shu-Chen
    Wang, Ching-Min
    Liu, Wei-Lun
    Lai, Chih-Cheng
    Contributors: 休閒保健管理系
    Keywords: Ventilator-associated event
    Diagnosis
    Definition
    Date: 2015-02
    Issue Date: 2016-04-19 19:05:21 (UTC+8)
    Publisher: Mosby-Elsevier
    Abstract: Objective: To investigate the concordance between novel and conventional surveillance paradigms for ventilator-associated pneumonia (VAP).
    Methods: This study was conducted at a regional teaching hospital in southern Taiwan with 5 acute intensive care units. To assess the validity of novel ventilator-associated event (VAE) surveillance, we retrospectively applied the VAE algorithm to analyze all VAP cases that were identified using conventional definitions between April 2010 and February 2014. Patient outcomes, including ventilator days, hospital stay lengths, and in-hospital mortality were recorded.
    Results: Among 165 episodes of conventional VAP, 55 (33.3%), 40 (24.2%), 20 (12.1%), and 2 (1.2%) episodes were classified as a ventilator-associated condition, an infection-related ventilator-associated complication, possible VAP, and probable VAP, respectively, according to the new VAE algorithm. Changes in positive end-expiratory pressure and inspired oxygen fraction levels during the development of VAP were significant higher among each VAE category than for conventional VAP (all P < .001). In-hospital mortality was significantly higher among patients with ventilator-associated condition than for patients with conventional VAP (P = .0185).
    Conclusions: In our study population, novel VAE surveillance only detected one-third of conventional VAP cases. Thus, more studies are needed to further validate VAE surveillance compared with conventional VAP by using strong microbiologic criteria, particularly bronchoalveolar lavage with a protected specimen brush for diagnosing VAP
    Relation: American Journal of Infection Control, v.43 n.2, pp.133-136
    Appears in Collections:[Dept. of Recreation and Health-Care Management] Periodical Articles

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