Antioxidant, Anti-Tyrosinase and Anti-Inflammatory Activities of Oil Production Residues from Camellia tenuifloria

doi:10.3390/ijms161226184

CNU IR > Pharmacy and Science > Dept. of Health and Nutrition (including master's program) > Periodical Articles > Item 310902800/29693

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/29693

Title:	Antioxidant, Anti-Tyrosinase and Anti-Inflammatory Activities of Oil Production Residues from Camellia tenuifloria
Authors:	Chiou, Shu-Yuan Ha, Choi-Lan Wu, Pei-Shan Yeh, Chiu-Ling Su, Ying-Shan Li, Man-Po Wu, Ming-Jiuan
Contributors:	保健營養系生物科技系
Keywords:	Camellia tenuifloria monophenolase diphenolase iNOS macrophages
Date:	2015-12
Issue Date:	2016-04-19 19:04:51 (UTC+8)
Publisher:	Mdpi Ag
Abstract:	Camellia tenuifloria is an indigenous Camellia species used for the production of camellia oil in Taiwan. This study investigated for the first time the potential antioxidant, anti-tyrosinase and anti-inflammatory activities of oil production byproducts, specifically those of the fruit shell, seed shell, and seed pomace from C. tenuifloria. It was found that the crude ethanol extract of the seed shell had the strongest DPPH scavenging and mushroom tyrosinase inhibitory activities, followed by the fruit shell, while seed pomace was the weakest. The IC50 values of crude extracts and fractions on monophenolase were smaller than diphenolase. The phenolic-rich methanol fraction of seed shell (SM) reduced nitric oxide (NO) production, and inducible nitric oxide synthase (iNOS) expression in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. It also repressed the expression of IL-1, and secretion of prostaglandin E-2 (PGE(2)) and IL-6 in response to LPS. SM strongly stimulated heme oxygenase 1 (HO-1) expression and addition of zinc protoporphyrin (ZnPP), a HO-1 competitive inhibitor, reversed the inhibition of NO production, indicating the involvement of HO-1 in its anti-inflammatory activity. The effects observed in this study provide evidence for the reuse of residues from C. tenuifloria in the food additive, medicine and cosmetic industries.
Relation:	International Journal of Molecular Sciences, v.16 n.12, pp.29522-29541
Appears in Collections:	[Dept. of Biotechnology (including master's program)] Periodical Articles [Dept. of Health and Nutrition (including master's program)] Periodical Articles

Files in This Item:

File	Description	Size	Format
29693.pdf		2717Kb	Adobe PDF	542	View/Open
index.html		0Kb	HTML	1689	View/Open

Loading...