English  |  正體中文  |  简体中文  |  Items with full text/Total items : 17744/20032 (89%)
Visitors : 7292236      Online Users : 302
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/29638

    標題: Epidemiology and prognostic factors of candidemia in elderly patients
    作者: Tang, Hung-Jen
    Liu, Wei-Lun
    Lin, Hsin-Lan
    Lai, Chih-Cheng
    貢獻者: 保健營養系
    關鍵字: cancer
    candida albicans
    日期: 2015-06
    上傳時間: 2016-04-19 19:02:54 (UTC+8)
    出版者: Wiley-Blackwell
    摘要: AimThe present retrospective study was carried out to investigate the epidemiological characteristics and the prognostic factors of candidemia among elderly patients.MethodsFrom 2009 to 2012, elderly patients with candidemia were identified at the Chi Mei medical center, a 900-bed regional hospital in southern Taiwan, and their medical records retrospectively reviewed.ResultsDuring the 4-year period, a total of 175 episodes of candidemia among elderly patients were identified. The patients ranged in age from 65 to 98years (mean 76.4years) and the mean (standard deviation) Charlson Comorbidity Index score was 7.6 (+/- 2.7). Cancer was the most common underlying disease (n=127, 72.6%), followed by diabetes mellitus (n=69, 39.4%). Candida albicans (n=96, 54.9%) was the most common pathogen, followed by C.tropicalis (n=39, 22.3%), C.parapsilosis (n=24, 13.7%), C.glabrata (n=22, 12.6%), C.guilliermondii (n=2, 1.1%) and Candida species (n=3, 1.7%). The ratio of C.albicans causing candidemia was significantly higher in young-old than old-old patients (64.1% vs 47.4%, P=0.027). The overall in-hospital mortality was 50.3%. Multivariate analysis showed that the in-hospital mortality was only significantly associated with jaundice (P=0.004), no use of antifungal agent (P=0.021) and intensive care unit admission (P<0.001).ConclusionsCandidemia can develop in elderly patients, especially patients with cancer or other risk factors. C.albicans is the most common Candida species causing candidemia among elderly patients, followed by C.tropicalis. The mortality of candidemia among elderly patients remains high. Geriatr Gerontol Int 2015; 15: 688-693.
    關聯: Geriatrics & Gerontology International, v.15 n.6, pp.688-693
    Appears in Collections:[保健營養系(所) ] 期刊論文

    Files in This Item:

    File Description SizeFormat

    All items in CNU IR are protected by copyright, with all rights reserved.

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback