Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/28698
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    標題: Simultaneous Determination of Antidiabetic Thiazolidinediones Using Flow Through Voltammetric Sensor
    作者: Wang, Lai-Hao
    Song, Yan-Lin
    貢獻者: 醫藥化學系
    關鍵字: Voltammetric sensor
    thiazolidine-2, 4-diones (TZDs)
    antidiabetic drugs
    日期: 2014
    上傳時間: 2015-05-06 21:25:35 (UTC+8)
    出版者: Bentham Science Publ Ltd
    摘要: We developed a method that uses flow through voltammetric sensor to quantitatively determine thiazolidine-2, 4-diones (TZDs) derivatives which are pioglitazone, rosiglitazone and troglitazone. The method uses a gold electrode. The dynamic range for determining thiazolidine-2, 4-diones (TZDs) is extended by more than two orders of magnitude. The quantification limits are 0.10, 23, 15, 0.005 ng for thiazolidine-2, 4-dione, pioglitazone, rosiglitazone and troglitazone, respectively. The method can be applied to the quantitatively determining pioglitazone and rosiglitazone in antidiabetic drugs. Findings using high-performance liquid chromatography with a flow-through voltammetric detector and ultraviolet detector are comparable.
    關聯: Current Pharmaceutical Analysis, v.10 n.4, pp.239-245
    显示于类别:[食藥產業暨檢測科技系(含五專)] 期刊論文

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