End-stage renal disease after hypertensive disorders in pregnancy

doi:10.1016/j.ajog.2013.09.027

Chia Nan University of Pharmacy & Science Institutional Repository > 藥理學院 > 藥學系(所) > 期刊論文 > Item 310902800/28561

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標題:	End-stage renal disease after hypertensive disorders in pregnancy
作者:	Wu, Chia-Chun Chen, Sheng-Hsien Ho, Chung-Han Liang, Fu-Wen Chu, Chin-Chen Wang, Hsien-Yi Lu, Yi-Hua
貢獻者:	休閒暨健康管理學院
關鍵字:	hypertensive disorder renal disease
日期:	2014-02
上傳時間:	2015-05-06 21:20:44 (UTC+8)
出版者:	Mosby-Elsevier
摘要:	OBJECTIVE: The purpose of this study was to determine the long-term postpartum risk of end-stage renal disease in women with hypertensive disorders in pregnancy. Although most women with hypertensive disorders in pregnancy recover after delivery, some may experience acute renal failure. STUDY DESIGN: We searched Taiwan's National Health Insurance Research Database to identify women with hypertensive disorders in pregnancies and deliveries between 1998 and 2002. All cases were followed for a maximum of 11 years (median, 9 years; interquartile range, 7.79-10.02 years) to estimate the incidence of end-stage renal disease; Cox regression analysis that was adjusted for potential confounding was used to determine the relative risk. RESULTS: Of the 13,633 women with hypertensive disorders in pregnancy, 46 experienced end-stage renal disease. Women with hypertensive disorders in pregnancy had a risk of end-stage renal disease that was 10.64 times greater than did women without them (95% confidence interval [CI], 7.53-15.05). The risk was highest in women with a history of preeclampsia superimposed on chronic hypertension (hazard ratio, 44.72; 95% CI, 22.59-88.51). Women with gestational hypertension had a higher risk of end-stage renal disease than did women without hypertensive disorders in pregnancy (hazard ratio, 5.82; 95% CI, 2.15-15.77). CONCLUSION: Women with hypertensive disorders in pregnancy have a higher risk of postpartum end-stage renal disease, regardless of which type of hypertensive disorder they have. Women with a history of hypertensive disorders in pregnancy are encouraged to have regular postpartum checkups, especially of renal function.
關聯:	American Journal of Obstetrics and Gynecology, v.210 n.2, 1470
顯示於類別:	[醫務管理系(所)] 期刊論文 [運動管理系] 期刊論文 [休閒保健管理系(所)] 期刊論文 [藥學系(所)] 期刊論文

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