資料載入中.....
|
請使用永久網址來引用或連結此文件:
https://ir.cnu.edu.tw/handle/310902800/28513
|
| 標題: | Asthma increases pulmonary thromboembolism risk: a nationwide population cohort study |
| 作者: | Chung, Wei-Sheng
Lin, Cheng-Li
Ho, Feng-Ming
Li, Ruei-Yuan
Sung, Fung-Chang
Kao, Chia-Hung
Yeh, Jun-Jun |
| 貢獻者: | 嬰幼兒保育系 |
| 關鍵字: | DEEP-VEIN THROMBOSIS
ENDOTHELIAL DYSFUNCTION
VENOUS THROMBOEMBOLISM
ALLERGEN CHALLENGE
EMBOLISM
COAGULATION
COPD
PREVALENCE
MORTALITY
DISEASE |
| 日期: | 2014-03 |
| 上傳時間: | 2015-05-06 21:19:00 (UTC+8) |
| 出版者: | European Respiratory Soc Journals Ltd |
| 摘要: | Studies on the association between asthma and pulmonary thromboembolism are considerably limited. We investigated whether pulmonary embolism is associated with asthma using a nationwide cohort study. We identified 31 356 patients with newly diagnosed asthma in 2002-2008 and 125 157 individuals without asthma randomly selected from the general population, frequency matched by age, sex and index year using the National Health Insurance Research Database. Both cohorts were followed-up until the end of 2010 to measure the incidence of pulmonary embolism. Cox proportional hazards regression analysis was used to measure the hazard ratio of pulmonary embolism for the asthmatic cohort, compared with the nonasthmatic cohort. We followed 186 182 person-years for asthmatic patients and 743 374 person-years for nonasthmatic subjects. The hazard ratio of pulmonary embolism was 3.24 for the asthmatic cohort, compared with the nonasthmatic cohort after adjusting for sex, age, comorbidities and oestrogen supplementation. The risk of developing pulmonary embolism significantly increased with the increased frequency of asthma exacerbation and hospitalisation. This nationwide cohort study suggests that the risk of developing pulmonary embolism is significantly increased in asthmatic patients compared to the general population. Frequent asthma exacerbation and hospitalisation are significantly associated with pulmonary embolism risk. |
| 關聯: | European Respiratory Journal, v.43 n.3, pp.801-807 |
| 顯示於類別: | [嬰幼兒保育系] 期刊論文
|
文件中的檔案:
| 檔案 |
描述 |
大小 | 格式 | 瀏覽次數 |
|---|
| 28513.pdf | | 304Kb | Adobe PDF | 1377 | 檢視/開啟 | | index.html | | 0Kb | HTML | 2290 | 檢視/開啟 |
|
在CNU IR中所有的資料項目都受到原著作權保護.
|
