Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/27930
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    標題: Sudden sensorineural hearing loss is correlated with an increased risk of acute myocardial infarction: A population-based cohort study
    作者: Lin, Charlene
    Lin, Shih-Wei
    Lin, Yung-Song
    Weng, Shih-Feng
    Lee, Tsung-Ming
    貢獻者: 醫務管理系
    關鍵字: Sudden Hearing Loss
    Acute Myocardial Infarction
    Sudden Sensorineural Hearing Loss
    日期: 2013-09
    上傳時間: 2014-05-26 10:49:28 (UTC+8)
    出版者: Wiley-Blackwell
    摘要: Objectives/Hypothesis Previous studies have indicated that hypercholesterolemia and a high burden of cardiovascular risk factors are associated with the development of sudden sensorineural hearing loss (SSHL). The purpose of this study was to test the hypothesis that SSHL is a risk factor for the development of myocardial infarction (MI).Study Design A retrospective cohort study.Methods Using the Taiwan Longitudinal Health Insurance Database, we compared patients diagnosed with SSHL between January 1, 2001, and December 31, 2006, (N = 44,830) with age-matched controls (1:1) (N = 44,830). We followed up on each patient until the end of 2009 to evaluate the incidence of MI for a minimum period of 3 years after their initial SSHL diagnosis.Results We found that after adjusting for potential confounds with an adjusted hazard ratio (HR) of 1.254 (95% confidence interval, 1.092-1.440, P < 0.05), patients with SSHL were more likely to suffer MI than the control population. When stratified by patient age, the incidence of MI was 1.62-fold and 1.28-fold higher for SSHL-diagnosed patients aged between 50 and 64 years and those aged 65 years (P = 0.0064 and P = 0.0001), respectively, than in the non-SSHL group.Conclusions SSHL may confer an independent risk of MI. This observation may prompt the early detection and timely treatment of patients at a high risk of MI.
    關聯: Laryngoscope, v.123 n.9, pp.2254-2258
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