Sudden sensorineural hearing loss is correlated with an increased risk of acute myocardial infarction: A population-based cohort study

doi:10.1002/lary.23837

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Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/27930

Title:	Sudden sensorineural hearing loss is correlated with an increased risk of acute myocardial infarction: A population-based cohort study
Authors:	Lin, Charlene Lin, Shih-Wei Lin, Yung-Song Weng, Shih-Feng Lee, Tsung-Ming
Contributors:	醫務管理系
Keywords:	Sudden Hearing Loss Acute Myocardial Infarction Sudden Sensorineural Hearing Loss
Date:	2013-09
Issue Date:	2014-05-26 10:49:28 (UTC+8)
Publisher:	Wiley-Blackwell
Abstract:	Objectives/Hypothesis Previous studies have indicated that hypercholesterolemia and a high burden of cardiovascular risk factors are associated with the development of sudden sensorineural hearing loss (SSHL). The purpose of this study was to test the hypothesis that SSHL is a risk factor for the development of myocardial infarction (MI).Study Design A retrospective cohort study.Methods Using the Taiwan Longitudinal Health Insurance Database, we compared patients diagnosed with SSHL between January 1, 2001, and December 31, 2006, (N = 44,830) with age-matched controls (1:1) (N = 44,830). We followed up on each patient until the end of 2009 to evaluate the incidence of MI for a minimum period of 3 years after their initial SSHL diagnosis.Results We found that after adjusting for potential confounds with an adjusted hazard ratio (HR) of 1.254 (95% confidence interval, 1.092-1.440, P < 0.05), patients with SSHL were more likely to suffer MI than the control population. When stratified by patient age, the incidence of MI was 1.62-fold and 1.28-fold higher for SSHL-diagnosed patients aged between 50 and 64 years and those aged 65 years (P = 0.0064 and P = 0.0001), respectively, than in the non-SSHL group.Conclusions SSHL may confer an independent risk of MI. This observation may prompt the early detection and timely treatment of patients at a high risk of MI.
Relation:	Laryngoscope, v.123 n.9, pp.2254-2258
Appears in Collections:	[Dept. of Hospital and Health (including master's program)] Periodical Articles

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